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MS-DRG 181 · MDC 04 · Medical

MS-DRG 181: Respiratory Neoplasms with CC

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: IPPS Table 5 FY2027 final rule (effective October 1, 2026); Definitions Manual v44 (effective October 1, 2026). Next CMS release: April 1, 2027 (v44.1 mid-year update), then the FY2028 final rule in August 2027.

Key facts for DRG 181

FY2027 relative weight
1.0930
Higher than 27% of all MS-DRGs
Change vs FY2026
+2.1%
FY2026 weight 1.0710
Geometric mean LOS
3.1 days
Arithmetic mean 4.1 days
MDC
04
Assignment of Diagnosis Codes
Severity level
with CC (complication or comorbidity)
Transfer policy
Not a transfer DRG

TL;DR

MS-DRG 181 is a medical group in MDC 04 (Assignment of Diagnosis Codes) at the middle severity level of its family. CMS assigns it a FY2027 relative weight of 1.0930 with a geometric mean length of stay of 3.1 days and an arithmetic mean of 4.1. Its weight moved up 2.1% from FY2026 (1.0710). That weight is higher than 27% of all medical and surgical MS-DRGs. Its CC/MCC family (DRG 180, DRG 182) spans weights 0.7440 to 1.7800. The v44 Definitions Manual assigns it through 64 principal diagnosis codes.

What changed from FY2026 to FY2027

CMS recalibrates every MS-DRG weight annually from the prior year's MedPAR claims. For DRG 181 the FY2027 relative weight is 1.0930 against 1.0710 in FY2026, a rise of 2.05%, which exceeds the 2% threshold worth re-checking in contract models.

FY2026 versus FY2027 payment factors for MS-DRG 181
MetricFY2026FY2027Change
Relative weight1.07101.0930+0.0220
Geometric mean LOS (days)3.13.1+0.0
Arithmetic mean LOS (days)4.14.1+0.0
Weights shown are the FY2027 final values after the 10% cap on year-over-year reductions where applicable.

CC and MCC family

DRG 181 shares its base definition with 2 other MS-DRGs split by severity. The family's weights span 0.7440 to 1.7800, a 2.39× spread, which is the payment effect of documenting qualifying complications and comorbidities.

MS-DRGs in the same base group as DRG 181
DRGTitleFY2027 weightGMLOS
180Respiratory Neoplasms with MCC1.78004.7
181Respiratory Neoplasms with CC1.09303.1
182Respiratory Neoplasms without CC/MCC0.74402.0

Grouper logic (v44 Definitions Manual)

Principal Diagnosis: 64 ICD-10 codes drive assignment to this group; the first 12 are shown.

Principal Diagnosis codes assigned to DRG 181 (sample)
ICD-10 codeDescription
C33Malignant neoplasm of trachea
C3400Malignant neoplasm of unspecified main bronchus
C3401Malignant neoplasm of right main bronchus
C3402Malignant neoplasm of left main bronchus
C3410Malignant neoplasm of upper lobe, unspecified bronchus or lung
C3411Malignant neoplasm of upper lobe, right bronchus or lung
C3412Malignant neoplasm of upper lobe, left bronchus or lung
C342Malignant neoplasm of middle lobe, bronchus or lung
C3430Malignant neoplasm of lower lobe, unspecified bronchus or lung
C3431Malignant neoplasm of lower lobe, right bronchus or lung
C3432Malignant neoplasm of lower lobe, left bronchus or lung
C3480Malignant neoplasm of overlapping sites of unspecified bronchus and lung

Documentation and denial exposure

As a medical DRG, assignment depends on the principal diagnosis sequenced from the attending's documentation; a secondary condition sequenced first, or a symptom code in place of the confirmed diagnosis, changes the MDC or the DRG. Because this family splits by severity, auditors target CC and MCC capture: each secondary diagnosis must be documented as present, monitored, evaluated or treated during the stay to survive a DRG-validation review. Typical inpatient denial codes for this group: CARC 16 (claim lacks information needed to group the stay), CARC 50 (the admission or procedure is judged not medically necessary), CARC 97 (a service is bundled into the DRG payment).

How QuickIntell uses DRG 181 data

QuickCode groups inpatient encounters against the current v44 logic, flags CC and MCC candidates that lack supporting documentation, and shows the weight difference across the family before the claim drops. QuickScribe captures the attending's language that supports severity, and QuickRCM works DRG-validation denials with the grouper evidence attached.

Frequently asked questions — DRG 181

What is MS-DRG 181?

MS-DRG 181 is "Respiratory Neoplasms with CC", a medical Medicare Severity Diagnosis-Related Group in MDC 04, Assignment of Diagnosis Codes. Medicare pays inpatient stays grouped here at the hospital's base rate multiplied by the DRG relative weight.

What is the FY2027 relative weight for DRG 181?

The FY2027 relative weight is 1.0930 (IPPS final rule Table 5, effective October 1, 2026). In FY2026 it was 1.0710, a change of +2.1%.

What is the average length of stay for DRG 181?

CMS reports a geometric mean length of stay of 3.1 days and an arithmetic mean of 4.1 days for FY2027. The geometric mean is used for transfer-payment calculations.

Which DRGs are in the same CC/MCC family as 181?

DRG 180 (Respiratory Neoplasms with MCC, weight 1.7800); DRG 182 (Respiratory Neoplasms without CC/MCC, weight 0.7440). The family's weights range from 0.7440 to 1.7800, so documented complications and comorbidities change payment materially.

What documentation supports the severity level of DRG 181?

DRG 181 is reached when the stay carries a secondary diagnosis from the CMS Complication or Comorbidity list but none from the MCC list. Common CC captures include chronic kidney disease stage 3 and above, uncontrolled diabetes with manifestations, malnutrition of specified severity and heart failure of a stated type. Each must be documented by the treating clinician and show clinical relevance in the record; a condition listed only in the problem list without assessment is the most frequent reason a CC is removed on audit and the stay drops to the base DRG.

Which codes group to DRG 181?

The v44 Definitions Manual lists 64 principal diagnosis codes for this group. Examples from the principal diagnosis list: C33 (Malignant neoplasm of trachea); C3400 (Malignant neoplasm of unspecified main bronchus); C3401 (Malignant neoplasm of right main bronchus); C3402 (Malignant neoplasm of left main bronchus).

Is DRG 181 a post-acute transfer DRG?

No. DRG 181 is not on the FY2027 post-acute care transfer list, so the transfer per-diem policy does not apply to it.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from the CMS IPPS FY2027 final rule (Table 5) and the v44 ICD-10 MS-DRG Definitions Manual. Relative weights are national factors; actual payment depends on each hospital's wage-adjusted base rate, add-ons, outliers and transfer adjustments. Nothing here is legal, clinical or billing advice; verify grouping against your encoder and the published CMS files.