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ICD-10-CM I82.459: Acute embolism and thrombosis of unspecified peroneal vein

I82.459 is the billable ICD-10-CM code for acute embolism and thrombosis of unspecified peroneal vein, in category I82 (Other venous embolism and thrombosis) of the Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified section. As a principal diagnosis it groups to MS-DRG 299 Peripheral Vascular Disorders with MCC, MS-DRG 300 Peripheral Vascular Disorders with CC, MS-DRG 301 Peripheral Vascular Disorders without CC/MCC (MDC 05 MDC 05: Diseases and Disorders of the Circulatory System). It maps to HCC 267 (Deep Vein Thrombosis and Pulmonary Embolism) in CMS-HCC V28. As a secondary diagnosis it is a CC, excluded with 201 principal diagnoses. 7 LCD billing and coding articles list it as covered.

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: ICD-10-CM code descriptions: FY2027 (effective October 1, 2026); IPPS Table 5 (MS-DRG weights): v44 FY2027 (final rule + CN3) (effective October 1, 2026); ICD-10-CM to HCC mapping: PY2027 initial ICD-10-CM mappings (dates of service 2026) (payment year 2027); Medicare Coverage Database billing and coding articles: MCD release October 8, 2026 (effective October 4, 2026). Next CMS release: FY2028 code files, effective October 1, 2027 for the ICD-10-CM code descriptions; FY2028 final rule (August 2027), effective October 1, 2027; an April 1 interim grouper update when CMS issues one for the IPPS Table 5 (MS-DRG weights); PY2028 advance notice (February 2027) and the PY2027 midyear final mapping (spring 2027) for the ICD-10-CM to HCC mapping; weekly, every Thursday for the Medicare Coverage Database billing and coding articles.

Code
I82.459
billable FY2027 ICD-10-CM code
Category
I82 Other venous embolism and thrombosis
Chapter
9: Diseases of the circulatory system (I00-I99)
CC/MCC (MS-DRG v44)
CC
CMS-HCC V28
HCC 267
POA reporting
Required

Tabular list notes for I82.459

The tabular list has no notes on I82.459 itself; the notes below apply from its parent headings.

Inherited from I82 (Other venous embolism and thrombosis)

Excludes2 (not part of this condition, may be coded together)
  • venous embolism and thrombosis (of):
  • cerebral (I63.6, I67.6)
  • coronary (I21-I25)
  • intracranial and intraspinal, septic or NOS (G08)
  • intracranial, nonpyogenic (I67.6)
  • intraspinal, nonpyogenic (G95.1)
  • mesenteric (K55.0-)
  • portal (I81)
  • pulmonary (I26.-)
Code first
  • venous embolism and thrombosis complicating:
  • abortion, ectopic or molar pregnancy (O00-O07, O08.7)
  • pregnancy, childbirth and the puerperium (O22.-, O87.-)

MS-DRG grouping when I82.459 is the principal diagnosis

MS-DRG v44 groups for I82.459 as principal diagnosis
MDCMS-DRGs
05 MDC 05: Diseases and Disorders of the Circulatory System299300301

The final group also depends on procedures, secondary diagnoses and discharge status; the MS-DRG lookup for I82.459 shows the full grouping logic.

CC/MCC status and inpatient edits

As a secondary diagnosis, I82.459 is a CC under MS-DRG v44, unless the principal diagnosis is one of the 201 codes in its exclusion list. Check I82.459 against a principal diagnosis.

  • Present on admission: a POA indicator is required on inpatient claims.
  • Hospital-acquired condition: HAC 10 Deep Vein Thrombosis (DVT) / Pulmonary Embolism (PE) with Total Knee or Hip Replacement.
  • Medicare Code Editor: unspecified code where a laterality-specific code exists.

CMS-HCC V28 risk adjustment

In the PY2027 mapping, I82.459 maps to HCC 267 (Deep Vein Thrombosis and Pulmonary Embolism). The HCC lookup shows the RAF weight and the hierarchy.

LCD billing and coding articles that list I82.459

7 current Medicare billing and coding articles list I82.459 among the diagnoses that support medical necessity for the services they cover.

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Frequently asked questions

What does ICD-10-CM I82.459 mean?

I82.459 means acute embolism and thrombosis of unspecified peroneal vein. It is one of 25 billable codes under I82, other venous embolism and thrombosis.

Which MS-DRG does I82.459 group to?

As the principal diagnosis, I82.459 groups to MS-DRG 299 Peripheral Vascular Disorders with MCC, MS-DRG 300 Peripheral Vascular Disorders with CC, MS-DRG 301 Peripheral Vascular Disorders without CC/MCC (MDC 05 MDC 05: Diseases and Disorders of the Circulatory System) under MS-DRG v44, before procedures and secondary diagnoses are applied.

Does I82.459 map to an HCC?

Yes: HCC 267, Deep Vein Thrombosis and Pulmonary Embolism, in the PY2027 CMS-HCC V28 mapping.

Is I82.459 a CC or MCC?

I82.459 is a CC under MS-DRG v44; 201 principal diagnoses exclude it.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

The descriptor and notes are reproduced from the FY2027 ICD-10-CM files; MS-DRG, CC/MCC and HCC facts come from the CMS FY2027 and PY2027 tables. Code from the medical record and the ICD-10-CM Official Guidelines. Not legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.