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HCPCS G0483 · Level II · G code

G0483: Drug test(s), definitive, HCPCS Level II G code

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: HCPCS Level II file: October 2026 (effective October 1, 2026); PFS relative value file: RVU26D, released August 26, 2026 (effective October 1, 2026); Clinical Laboratory Fee Schedule: 26CLABQ4 (CY2026 Q4) (effective October 1, 2026); NCCI MUE tables: 2026 Q4 (effective October 1, 2026); NCCI PTP edits: v323r0 (2026 Q4) (effective October 1, 2026); OPPS Addendum B: October 2026 (effective October 1, 2026); Medicare Coverage Database LCD export: MCD release October 8, 2026 (effective October 4, 2026). Next CMS release: January 1, 2027 (quarterly update) for the HCPCS Level II file and Clinical Laboratory Fee Schedule and NCCI MUE tables and NCCI PTP edits and OPPS Addendum B; RVU27A with the CY2027 PFS final rule, effective January 1, 2027 for the PFS relative value file; weekly, every Thursday for the Medicare Coverage Database LCD export.

Key facts for G0483

Medicare payment
$246.92
CLFS national limitation amount
Coverage code
C
carrier judgment, so the Medicare contractor decides coverage
Practitioner MUE
1
MAI 2
OPPS status
SI Q4
Conditionally packaged laboratory services
NCCI PTP pairs
99
99 hospital outpatient
LCDs and articles
7 / 7

TL;DR

G0483 is a Level II code from the G section (procedures and professional services, temporary), in use since 2016: "Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performed". The 2026 Q4 clinical laboratory fee schedule pays G0483 $246.92 (national limitation amount). MUE limits for G0483: practitioner 1 (MAI 2, Code Descriptor / CPT Instruction); hospital outpatient 1 (MAI 2, Code Descriptor / CPT Instruction). In the NCCI PTP files v323r0 G0483 appears in 4 practitioner pairs as column 2 and 95 as column 1 (most often with 0007U, 0082U, 0227U), and in 4 hospital outpatient pairs as column 2 and 95 as column 1. 7 active LCDs and 7 billing and coding articles list G0483 across 26 states plus DC and 2 territories: L34645 (Urine Drug Testing), L35006 (Controlled Substance Monitoring and Drugs of Abuse Testing), A54799, A55001. OPPS status indicator Q4: Conditionally packaged laboratory services. HCPCS record: BETOS T1H (lab tests - other (non-Medicare fee schedule)); pricing indicator 21; type of service 5 (diagnostic laboratory). 4 other active codes open with "Drug test"; related codes: G0481, G0480, G0659, G0482.

G0483 descriptor and code status

The October 2026 HCPCS Level II file describes G0483 as “Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performed”. It sits in the G section (procedures and professional services, temporary), listed with the other G codes. Although searches often call it the "G0483 CPT code", G0483 is a HCPCS Level II code maintained by CMS, not an AMA CPT code; both go in the same procedure-code field on the claim.

HCPCS file attributes of G0483
FieldValue
Short descriptorDrug test def 22+ classes
Added to HCPCS2016-01-01
Last actionN (no maintenance), effective 2017-01-01
Coverage codeC: carrier judgment, so the Medicare contractor decides coverage
Pricing indicator21: clinical lab fee schedule, subject to the national limitation amount
BETOS categoryT1H: lab tests - other (non-Medicare fee schedule)
Type of service5: diagnostic laboratory

Medicare payment for G0483

The 2026 Q4 clinical laboratory fee schedule pays G0483 $246.92 (national limitation amount). The amounts below are national figures from the October 2026 CMS files; the contractor applies the locality, rural or state adjustment and the beneficiary's cost sharing.

Physician fee schedule (RVU26D)

Status X: statutory exclusion: not a physician service under the fee schedule. Global period XXX (global surgery concept does not apply); PC/TC indicator 9 (professional/technical concept does not apply).

Clinical Laboratory Fee Schedule (26CLABQ4)

G0483 is paid at $246.92 (national limitation amount). Laboratory fee schedule payments carry no beneficiary coinsurance or deductible.

Hospital outpatient (OPPS Addendum B)

Status indicator Q4 (Conditionally packaged laboratory services), with no separate OPPS payment rate.

Medically Unlikely Edits for G0483

MUE limits for G0483: practitioner 1 (MAI 2, Code Descriptor / CPT Instruction); hospital outpatient 1 (MAI 2, Code Descriptor / CPT Instruction). The practitioner MUE is a date-of-service policy edit: units above the limit deny even when split across lines, and appeals rarely succeed.

MUE values for G0483 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services12 Date of Service Edit: PolicyCode Descriptor / CPT Instruction
Facility outpatient hospital12 Date of Service Edit: PolicyCode Descriptor / CPT Instruction

The MUE lookup for G0483 shows every setting next to any other code on the same claim.

NCCI edits and add-on rules

In the practitioner PTP file v323r0, G0483 is the column-2 (bundled) code in 4 active pairs, 0% of which allow a modifier and the column-1 code in 95 (26% modifier-allowed); 16 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Mutually exclusive procedures.

Column-1 codes most often paired with G0483 (practitioner)
Column-1 codePairs
0007U (CPT; descriptor licensed by AMA)1
0082U (CPT; descriptor licensed by AMA)1
0227U (CPT; descriptor licensed by AMA)1
0328U (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into G0483 (practitioner)
Column-2 codePairs
0011U (CPT; descriptor licensed by AMA)1
0051U (CPT; descriptor licensed by AMA)1
0054U (CPT; descriptor licensed by AMA)1
0093U (CPT; descriptor licensed by AMA)1
0110U (CPT; descriptor licensed by AMA)1
0116U (CPT; descriptor licensed by AMA)1
0119U (CPT; descriptor licensed by AMA)1
0251U (CPT; descriptor licensed by AMA)1

In the hospital outpatient PTP file v323r0, G0483 is the column-2 (bundled) code in 4 active pairs, 0% of which allow a modifier and the column-1 code in 95 (26% modifier-allowed); 21 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Mutually exclusive procedures.

Column-1 codes most often paired with G0483 (hospital outpatient)
Column-1 codePairs
0007U (CPT; descriptor licensed by AMA)1
0082U (CPT; descriptor licensed by AMA)1
0227U (CPT; descriptor licensed by AMA)1
0328U (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into G0483 (hospital outpatient)
Column-2 codePairs
0011U (CPT; descriptor licensed by AMA)1
0051U (CPT; descriptor licensed by AMA)1
0054U (CPT; descriptor licensed by AMA)1
0093U (CPT; descriptor licensed by AMA)1
0110U (CPT; descriptor licensed by AMA)1
0116U (CPT; descriptor licensed by AMA)1
0119U (CPT; descriptor licensed by AMA)1
0251U (CPT; descriptor licensed by AMA)1

G0483 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Pair counts show exposure, not the answer for one claim. Check G0483 against a second code to see whether the pair bundles and whether a modifier can separate the services.

Medicare coverage policies for G0483

7 active Local Coverage Determinations and 7 billing and coding articles list G0483. Each applies only in its contractor's jurisdiction, and the article carries the diagnosis codes that support the item or service.

Billing and Coding Articles listing G0483
ArticleTitleContractor(s)Related LCD
A54799Billing and Coding: Urine Drug TestingPalmetto GBAL35724
A55001Billing and Coding: Urine Drug TestingNoridian Healthcare Solutions, LLCL36668, L39586
A56645Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse TestingNovitas Solutions, Inc.L35006
A56818Billing and Coding: Urine Drug TestingCGS Administrators, LLCL36029
A56915Billing and Coding: Urine Drug TestingWisconsin Physicians Service Insurance CorporationL34645, L39622
A57077Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse TestingFirst Coast Service Options, Inc.L36393
A59416Billing and Coding: Urine Drug TestingWellpoint FederalL39611

Denials to expect on G0483

the diagnosis or documentation does not meet the LCD or billing article that lists G0483

units of G0483 exceed the practitioner MUE of 1 per date of service

the modifier reported is inconsistent with the code

the claim lacks information needed to adjudicate the line, such as an order, NPI or required modifier

Where QuickIntell fits for G0483 claims

QuickCode supports qualified coder review of units, modifiers and NCCI pairs for G0483 before the claim leaves, and QuickRCM carries claim readiness and the denial follow-up when an edit or coverage policy is missed.

Frequently asked questions: HCPCS G0483

What does HCPCS code G0483 describe?

"Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performed" (short descriptor "Drug test def 22+ classes"), in the G section (procedures and professional services, temporary). Added 2016-01-01; last action N (no maintenance) effective 2017-01-01.

Is G0483 a CPT code?

No: CMS maintains G0483 in HCPCS Level II, while the AMA maintains CPT. People do search "G0483 CPT code", and it goes in the same procedure-code field.

What does Medicare pay for G0483?

The 2026 Q4 clinical laboratory fee schedule pays G0483 $246.92 (national limitation amount).

How many units of G0483 can be billed per day?

MUE limits for G0483: practitioner 1 (MAI 2, Code Descriptor / CPT Instruction); hospital outpatient 1 (MAI 2, Code Descriptor / CPT Instruction). For the practitioner MUE (MAI 2), units above 1 deny for the whole day as a policy limit; denials arrive as CARC 151.

Does Medicare cover G0483?

Coverage code C (carrier judgment, so the Medicare contractor decides coverage). 7 active LCDs and 7 billing and coding articles list G0483 across 26 states plus DC and 2 territories: L34645 (Urine Drug Testing), L35006 (Controlled Substance Monitoring and Drugs of Abuse Testing), A54799, A55001.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

This page is an operational reference compiled from CMS publications: the HCPCS Level II file, the physician, DMEPOS and clinical laboratory fee schedules, OPPS and ASC addenda, NCCI MUE, PTP and add-on edit tables and the Medicare Coverage Database. Amounts are Medicare national figures before locality and state adjustment; Medicaid and commercial payers set their own. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.