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HCC 115: Specified Immunodeficiencies and White Blood Cell Disorders

HCC 115, Specified Immunodeficiencies and White Blood Cell Disorders, is one of the 115 payment categories in the CMS-HCC V28 model. 19 ICD-10-CM codes map to it in the payment year 2027 mapping, and a documented diagnosis in the category adds a relative factor of 0.565 to the risk score of a community, non-dual, aged beneficiary (0.692 disabled, 0.691 institutional). It is overridden when a more severe category in its hierarchy is present (HCC 114).

QuickIntell editorial content · Legacy registry date · Review not verified

Data effective
Data currency: ICD-10-CM to HCC mapping PY2027 initial (effective dates of service 2026, payment year 2027); CMS-HCC V28 model software V2826.115.T2 (effective payment year 2027). Next CMS release: PY2027 midyear final mapping (spring 2027) and PY2028 proposed model (February 2027).
Mapped ICD-10-CM codes
19
Factor, community non-dual aged
0.565
Factor, institutional
0.691
Hierarchy
Overridden by HCC 114

Relative factors by segment

Each segment is a separate regression; the factor is added to the beneficiary's demographic factors and other categories, then normalized and reduced by the coding intensity adjustment before it meets the plan's base rate. A factor of 1.000 equals the expected cost of an average beneficiary.

CMS-HCC V28 relative factors for HCC 115 by model segment
SegmentModel codeRelative factor
Community, non-dual, agedCNA_HCC1150.565
Community, non-dual, disabledCND_HCC1150.692
Community, full-benefit dual, agedCFA_HCC1150.438
Community, full-benefit dual, disabledCFD_HCC1150.498
Community, partial-benefit dual, agedCPA_HCC1150.302
Community, partial-benefit dual, disabledCPD_HCC1150.613
Long-term institutionalINS_HCC1150.691

Hierarchy

Hierarchical condition categories pay only the most severe manifestation of a disease. When HCC 114 (Common Variable and Combined Immunodeficiencies) is also documented for the same beneficiary, HCC 115 is dropped from the score.

ICD-10-CM codes that map to HCC 115

19 codes map to this category in the PY2027 initial mapping, concentrated in the D80 (5), D71 (4), D70 (2), D76 (2), D82 (2), D72 (1) code families. Descriptions are the CMS mapping descriptions for the FY2026 code set; a code that is deleted or split in the October code update stays valid for dates of service before the change.

ICD-10-CM codes mapped to HCC 115 in the CMS PY2027 initial mapping
ICD-10-CMDescription
D700Congenital agranulocytosis
D704Cyclic neutropenia
D71Functional disorders of polymorphonuclear neutrophils
D711Leukocyte adhesion deficiency
D718Other functional disorders of polymorphonuclear neutrophils
D719Functional disorders of polymorphonuclear neutrophils, unspecified
D720Genetic anomalies of leukocytes
D761Hemophagocytic lymphohistiocytosis
D763Other histiocytosis syndromes
D800Hereditary hypogammaglobulinemia
D802Selective deficiency of immunoglobulin A [IgA]
D803Selective deficiency of immunoglobulin G [IgG] subclasses
D804Selective deficiency of immunoglobulin M [IgM]
D805Immunodeficiency with increased immunoglobulin M [IgM]
D814Nezelof's syndrome
D820Wiskott-Aldrich syndrome
D821Di George's syndrome
D841Defects in the complement system
D8984IgG4-related disease

Where these codes sat in the V22 model

The V28 recalibration renumbered and regrouped categories; this table shows which legacy V22 categories the same ICD-10 codes belonged to, which is the quickest way to reconcile a V22-era HCC gap list with the current model.

V22 categories that the HCC 115 codes mapped to
V22 HCCCodes
4718
231

Capturing and defending the category

A category counts for a payment year when a mapped diagnosis is documented at least once during the data collection year by an acceptable provider type at a face-to-face or audio-video encounter, and when the note shows the condition was monitored, evaluated, assessed or treated. Chronic conditions do not carry forward: a category that is not re-documented in the year drops out of the score, which is why annual wellness visits and problem-list reconciliation are where most recapture happens. Risk adjustment data validation audits sample enrollees and ask for the medical record behind each submitted category; an unsupported category is removed and, under the extrapolation rules, the error rate is applied across the contract. The QuickIntell risk adjustment product surfaces suspected and unsupported categories from the chart, and the HCC hub lists every V28 category with its factor and code count.

Frequently asked questions

Which ICD-10 codes map to HCC 115?

19 ICD-10-CM codes map to HCC 115 in the CMS PY2027 initial mapping, for example D700 Congenital agranulocytosis; D704 Cyclic neutropenia; D71 Functional disorders of polymorphonuclear neutrophils; D711 Leukocyte adhesion deficiency. The full list is on this page; a code counts only when it is documented at a face-to-face or video encounter in the data collection year and supported by the record.

How much does HCC 115 add to a risk score?

The V28 relative factor for HCC 115 is 0.565 for a community, non-dual, aged beneficiary, 0.438 for full-benefit dual aged, 0.692 for non-dual disabled and 0.691 for long-term institutional members. A factor of 1.000 equals the expected annual cost of an average beneficiary, so the category's share of the payment follows the plan's base rate for that segment.

Does HCC 115 count together with related categories?

No. Within a hierarchy only the most severe category is paid. HCC 115 is dropped when HCC 114 (Common Variable and Combined Immunodeficiencies) is also present.

What has to be documented for HCC 115 to be valid?

The diagnosis must be recorded by an acceptable provider type during a face-to-face or audio-video encounter in the service year, with the note showing that the condition was monitored, evaluated, assessed or treated. Risk adjustment data validation audits recover payment for categories the record does not support, so the code on the claim and the assessment in the note must match.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-02. Verify against the primary file before billing or contracting decisions.

Disclaimer

Relative factors and mappings are reproduced from the CMS risk adjustment model files as an operational reference. Payment depends on the plan's base rate, normalization, the coding intensity adjustment and the enrollee's segment. Not legal, clinical or billing advice.