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ICD-10-CM category Z79: Long term (current) drug therapy

Category Z79 is a heading in chapter 21 (Factors influencing health status and contact with health services (Z00-Z99)), section Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99). It is not billable; report one of the 32 complete codes below.

Notes that apply to every Z79 code

Includes
  • long term (current) drug use for prophylactic purposes
Excludes2 (not part of this condition, may be coded together)
  • drug abuse and dependence (F11-F19)
  • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Code also
  • any therapeutic drug level monitoring (Z51.81)

Billable codes in Z79

Billable FY2027 ICD-10-CM codes in category Z79
CodeDescription
Z79.01Long term (current) use of anticoagulants
Z79.02Long term (current) use of antithrombotics/antiplatelets
Z79.1Long term (current) use of non-steroidal anti-inflammatories (NSAID)
Z79.2Long term (current) use of antibiotics
Z79.3Long term (current) use of hormonal contraceptives
Z79.4Long term (current) use of insulin
Z79.51Long term (current) use of inhaled steroids
Z79.52Long term (current) use of systemic steroids
Z79.60Long term (current) use of unspecified immunomodulators and immunosuppressants
Z79.61Long term (current) use of immunomodulator
Z79.620Long term (current) use of immunosuppressive biologic
Z79.621Long term (current) use of calcineurin inhibitor
Z79.622Long term (current) use of Janus kinase inhibitor
Z79.623Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
Z79.624Long term (current) use of inhibitors of nucleotide synthesis
Z79.630Long term (current) use of alkylating agent
Z79.631Long term (current) use of antimetabolite agent
Z79.632Long term (current) use of antitumor antibiotic
Z79.633Long term (current) use of mitotic inhibitor
Z79.634Long term (current) use of topoisomerase inhibitor
Z79.64Long term (current) use of myelosuppressive agent
Z79.69Long term (current) use of other immunomodulators and immunosuppressants
Z79.810Long term (current) use of selective estrogen receptor modulators (SERMs)
Z79.811Long term (current) use of aromatase inhibitors
Z79.818Long term (current) use of other agents affecting estrogen receptors and estrogen levels
Z79.82Long term (current) use of aspirin
Z79.83Long term (current) use of bisphosphonates
Z79.84Long term (current) use of oral hypoglycemic drugs
Z79.85Long-term (current) use of injectable non-insulin antidiabetic drugs
Z79.890Hormone replacement therapy
Z79.891Long term (current) use of opiate analgesic
Z79.899Other long term (current) drug therapy

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Codes from the FY2027 ICD-10-CM files (all chapters). Report the code that matches the documentation and the Official Guidelines; this list is not coding advice.