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ICD-10-CM category K21: Gastro-esophageal reflux disease

Category K21 is a heading in chapter 11 (Diseases of the digestive system (K00-K95)), section Diseases of esophagus, stomach and duodenum (K20-K31). It is not billable; report one of the 3 complete codes below.

Notes that apply to every K21 code

Excludes1 (never coded together)
  • newborn esophageal reflux (P78.83)

Billable codes in K21

Billable FY2027 ICD-10-CM codes in category K21
CodeDescription
K21.00Gastro-esophageal reflux disease with esophagitis, without bleeding
K21.01Gastro-esophageal reflux disease with esophagitis, with bleeding
K21.9Gastro-esophageal reflux disease without esophagitis

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Codes from the FY2027 ICD-10-CM files (all chapters). Report the code that matches the documentation and the Official Guidelines; this list is not coding advice.