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ICD-10-CM C64.2: Malignant neoplasm of left kidney, except renal pelvis

C64.2 is the billable ICD-10-CM code for malignant neoplasm of left kidney, except renal pelvis, in category C64 (Malignant neoplasm of kidney, except renal pelvis) of the Malignant neoplasms of urinary tract section. As a principal diagnosis it groups to MS-DRG 656 Kidney and Ureter Procedures for Neoplasm with MCC, MS-DRG 657 Kidney and Ureter Procedures for Neoplasm with CC, MS-DRG 658 Kidney and Ureter Procedures for Neoplasm without CC/MCC (MDC 11 MDC 11: Diseases and Disorders of the Kidney and Urinary Tract). It maps to HCC 22 (Bladder, Colorectal, and Other Cancers) in CMS-HCC V28. As a secondary diagnosis it is a CC, excluded with 27 principal diagnoses. 64 LCD billing and coding articles list it as covered.

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: ICD-10-CM code descriptions: FY2027 (effective October 1, 2026); IPPS Table 5 (MS-DRG weights): v44 FY2027 (final rule + CN3) (effective October 1, 2026); ICD-10-CM to HCC mapping: PY2027 initial ICD-10-CM mappings (dates of service 2026) (payment year 2027); Medicare Coverage Database billing and coding articles: MCD release October 8, 2026 (effective October 4, 2026). Next CMS release: FY2028 code files, effective October 1, 2027 for the ICD-10-CM code descriptions; FY2028 final rule (August 2027), effective October 1, 2027; an April 1 interim grouper update when CMS issues one for the IPPS Table 5 (MS-DRG weights); PY2028 advance notice (February 2027) and the PY2027 midyear final mapping (spring 2027) for the ICD-10-CM to HCC mapping; weekly, every Thursday for the Medicare Coverage Database billing and coding articles.

Code
C64.2
billable FY2027 ICD-10-CM code
Category
C64 Malignant neoplasm of kidney, except renal pelvis
Chapter
2: Neoplasms (C00-D49)
CC/MCC (MS-DRG v44)
CC
CMS-HCC V28
HCC 22
POA reporting
Required

Tabular list notes for C64.2

The tabular list has no notes on C64.2 itself; the notes below apply from its parent headings.

Inherited from C64 (Malignant neoplasm of kidney, except renal pelvis)

Excludes1 (never coded together)
  • malignant carcinoid tumor of the kidney (C7A.093)
  • malignant neoplasm of renal calyces (C65.-)
  • malignant neoplasm of renal pelvis (C65.-)

MS-DRG grouping when C64.2 is the principal diagnosis

MS-DRG v44 groups for C64.2 as principal diagnosis
MDCMS-DRGs
11 MDC 11: Diseases and Disorders of the Kidney and Urinary Tract656657658686687688

The final group also depends on procedures, secondary diagnoses and discharge status; the MS-DRG lookup for C64.2 shows the full grouping logic.

CC/MCC status and inpatient edits

As a secondary diagnosis, C64.2 is a CC under MS-DRG v44, unless the principal diagnosis is one of the 27 codes in its exclusion list. Check C64.2 against a principal diagnosis.

  • Present on admission: a POA indicator is required on inpatient claims.

CMS-HCC V28 risk adjustment

In the PY2027 mapping, C64.2 maps to HCC 22 (Bladder, Colorectal, and Other Cancers). The HCC lookup shows the RAF weight and the hierarchy.

LCD billing and coding articles that list C64.2

64 current Medicare billing and coding articles list C64.2 among the diagnoses that support medical necessity for the services they cover.

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Frequently asked questions

What does ICD-10-CM C64.2 mean?

C64.2 means malignant neoplasm of left kidney, except renal pelvis. It is one of 3 billable codes under C64, malignant neoplasm of kidney, except renal pelvis.

What can't be coded with C64.2?

Excludes1 at C64: malignant carcinoid tumor of the kidney (C7A.093); malignant neoplasm of renal calyces (C65.-); malignant neoplasm of renal pelvis (C65.-). These are never reported together with C64.2.

Which MS-DRG does C64.2 group to?

As the principal diagnosis, C64.2 groups to MS-DRG 656 Kidney and Ureter Procedures for Neoplasm with MCC, MS-DRG 657 Kidney and Ureter Procedures for Neoplasm with CC, MS-DRG 658 Kidney and Ureter Procedures for Neoplasm without CC/MCC (MDC 11 MDC 11: Diseases and Disorders of the Kidney and Urinary Tract) under MS-DRG v44, before procedures and secondary diagnoses are applied.

Does C64.2 map to an HCC?

Yes: HCC 22, Bladder, Colorectal, and Other Cancers, in the PY2027 CMS-HCC V28 mapping.

Is C64.2 a CC or MCC?

C64.2 is a CC under MS-DRG v44; 27 principal diagnoses exclude it.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

The descriptor and notes are reproduced from the FY2027 ICD-10-CM files; MS-DRG, CC/MCC and HCC facts come from the CMS FY2027 and PY2027 tables. Code from the medical record and the ICD-10-CM Official Guidelines. Not legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.