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ICD-10-CM category C22: Malignant neoplasm of liver and intrahepatic bile ducts

Category C22 is a heading in chapter 2 (Neoplasms (C00-D49)), section Malignant neoplasms of digestive organs (C15-C26). It is not billable; report one of the 8 complete codes below.

Notes that apply to every C22 code

Excludes1 (never coded together)
  • malignant neoplasm of biliary tract NOS (C24.9)
  • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Use additional code
  • code to identify:
  • alcohol abuse and dependence (F10.-)
  • hepatitis B (B16.-, B18.0-B18.1)
  • hepatitis C (B17.1-, B18.2)

Billable codes in C22

Billable FY2027 ICD-10-CM codes in category C22
CodeDescription
C22.0Liver cell carcinoma
C22.1Intrahepatic bile duct carcinoma
C22.2Hepatoblastoma
C22.3Angiosarcoma of liver
C22.4Other sarcomas of liver
C22.7Other specified carcinomas of liver
C22.8Malignant neoplasm of liver, primary, unspecified as to type
C22.9Malignant neoplasm of liver, not specified as primary or secondary

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Codes from the FY2027 ICD-10-CM files (all chapters). Report the code that matches the documentation and the Official Guidelines; this list is not coding advice.