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MDC 08: Diseases and Disorders of the Musculoskeletal System and Connective Tissue

106 MS-DRGs (72 surgical, 34 medical) with FY2027 relative weights averaging 2.7482. Click any DRG for its weight history, CC/MCC family, grouper code lists and denial exposure.

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective

MS-DRGs in MDC 08

Weights in this category range from 0.7120 (DRG 538) to 13.7380 (DRG 523); the change column compares FY2027 with FY2026.

MS-DRGs assigned to MDC 08 with FY2027 weights
DRGTitleTypeWeightGMLOSChange
400Knee Procedures with Principal Diagnosis of InfectionSurgical2.02505.8new
402Single Level Combined Anterior and Posterior Spinal Fusion Except CervicalSurgical4.09502.4+1.8%
403Hip or Knee Procedures with Principal Diagnosis of Periprosthetic Joint Infection with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical5.00509.0new
404Hip or Knee Procedures with Principal Diagnosis of Periprosthetic Joint Infection without MCCSurgical3.25204.6new
426Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical with MCCSurgical9.91906.7-10.0%
427Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical with CCSurgical6.70203.7-7.2%
428Multiple Level Combined Anterior and Posterior Spinal Fusion Except Cervical without CC/MCCSurgical5.92002.5+5.3%
429Combined Anterior and Posterior Cervical Spinal Fusion with MCCSurgical8.84109.5-1.9%
430Combined Anterior and Posterior Cervical Spinal Fusion without MCCSurgical5.89403.5+2.2%
447Multiple Level Spinal Fusion Except Cervical with MCCSurgical6.96608.1+4.3%
448Multiple Level Spinal Fusion Except Cervical without MCCSurgical4.35003.3+2.6%
449Revision of Hip or Knee ProsthesisSurgical3.30003.1new
450Single Level Spinal Fusion Except Cervical with MCCSurgical5.23406.3-1.8%
451Single Level Spinal Fusion Except Cervical without MCCSurgical3.26002.4+0.9%
456Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with MCCSurgical7.62109.9-9.3%
457Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with CCSurgical5.36704.5-10.0%
458Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection without CC/MCCSurgical4.03702.1-3.3%
461Bilateral or Multiple Major Joint Procedures of Lower Extremity with MCCSurgical4.97106.2-10.0%
462Bilateral or Multiple Major Joint Procedures of Lower Extremity without MCCSurgical2.85302.2+7.3%
463Wound Debridement or Skin Graft Except Hand for Musculoskeletal and Connective Tissue Disorders with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical5.13007.8-10.0%
464Wound Debridement or Skin Graft Except Hand for Musculoskeletal and Connective Tissue Disorders with CCSurgical3.17603.0+2.0%
465Wound Debridement or Skin Graft Except Hand for Musculoskeletal and Connective Tissue Disorders without CC/MCCSurgical2.48201.4+36.1%
469Major Hip and Knee Joint Replacement or Reattachment of Lower Extremity with MCC or Total Ankle ReplacementSurgical3.10803.3+2.5%
470Major Hip and Knee Joint Replacement or Reattachment of Lower Extremity without MCCSurgical1.95602.0+1.4%
471Cervical Spinal Fusion with MCCSurgical4.93607.0+2.2%
472Cervical Spinal Fusion with CCSurgical2.98102.5+1.2%
473Cervical Spinal Fusion without CC/MCCSurgical2.45301.6+0.5%
474Amputation for Musculoskeletal System and Connective Tissue Disorders with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical4.21309.7-1.9%
475Amputation for Musculoskeletal System and Connective Tissue Disorders with CCSurgical2.22506.0-2.2%
476Amputation for Musculoskeletal System and Connective Tissue Disorders without CC/MCCSurgical1.13502.6-3.8%
477Biopsies of Musculoskeletal System and Connective Tissue with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical3.40308.1-1.5%
478Biopsies of Musculoskeletal System and Connective Tissue with CCSurgical2.43405.3-1.0%
479Biopsies of Musculoskeletal System and Connective Tissue without CC/MCCSurgical1.85303.3-0.3%
480Hip and Femur Procedures Except Major Joint with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical2.92006.0+0.3%
481Hip and Femur Procedures Except Major Joint with CCSurgical2.12704.3+1.5%
482Hip and Femur Procedures Except Major Joint without CC/MCCSurgical1.64003.0+0.6%
483Major Joint or Limb Reattachment Procedures of Upper ExtremitiesSurgical2.89602.1+4.5%
488Knee Procedures without Principal Diagnosis of Infection with CC/MCCSurgical2.22004.6+25.5%
489Knee Procedures without Principal Diagnosis of Infection without CC/MCCSurgical1.31202.0+17.5%
492Lower Extremity and Humerus Procedures Except Hip, Foot and Femur with MCC or Insertion of Antibiotic-eluting Bone Void FillerSurgical3.69206.4+0.5%
493Lower Extremity and Humerus Procedures Except Hip, Foot and Femur with CCSurgical2.55304.2+0.7%
494Lower Extremity and Humerus Procedures Except Hip, Foot and Femur without CC/MCCSurgical2.02502.8+1.0%
495Local Excision and Removal of Internal Fixation Devices Except Hip and Femur with MCCSurgical3.33607.0-8.0%
496Local Excision and Removal of Internal Fixation Devices Except Hip and Femur with CCSurgical1.77802.8-1.4%
497Local Excision and Removal of Internal Fixation Devices Except Hip and Femur without CC/MCCSurgical1.17101.4-3.1%
498Local Excision and Removal of Internal Fixation Devices of Hip and Femur with CC/MCCSurgical3.18804.4+5.7%
499Local Excision and Removal of Internal Fixation Devices of Hip and Femur without CC/MCCSurgical2.16701.8+7.5%
500Soft Tissue Procedures with MCCSurgical3.36007.8+6.2%
501Soft Tissue Procedures with CCSurgical1.86604.1+6.8%
502Soft Tissue Procedures without CC/MCCSurgical1.43302.3+6.5%
503Foot Procedures with MCCSurgical2.77606.9-0.5%
504Foot Procedures with CCSurgical1.77504.0-5.0%
505Foot Procedures without CC/MCCSurgical1.77504.0-1.0%
506Major Thumb or Joint ProceduresSurgical1.21403.7-10.0%
507Major Shoulder or Elbow Joint Procedures with CC/MCCSurgical1.85705.1+2.8%
508Major Shoulder or Elbow Joint Procedures without CC/MCCSurgical1.36302.9-10.0%
510Shoulder, Elbow or Forearm Procedures, Except Major Joint Procedures with MCCSurgical3.12805.2+3.5%
511Shoulder, Elbow or Forearm Procedures, Except Major Joint Procedures with CCSurgical2.11803.5+1.9%
512Shoulder, Elbow or Forearm Procedures, Except Major Joint Procedures without CC/MCCSurgical1.70402.2+3.0%
513Hand or Wrist Procedures, Except Major Thumb or Joint Procedures with CC/MCCSurgical1.52103.8-3.4%
514Hand or Wrist Procedures, Except Major Thumb or Joint Procedures without CC/MCCSurgical1.02002.3-0.2%
515Other Musculoskeletal System and Connective Tissue O.R. Procedures with MCCSurgical3.18906.7+0.1%
516Other Musculoskeletal System and Connective Tissue O.R. Procedures with CCSurgical2.11804.0+1.9%
517Other Musculoskeletal System and Connective Tissue O.R. Procedures without CC/MCCSurgical1.57302.3+2.3%
518Back and Neck Procedures Except Spinal Fusion with MCC or Disc Device or NeurostimulatorSurgical3.73105.1-0.2%
519Back and Neck Procedures Except Spinal Fusion with CCSurgical2.03603.2+1.8%
520Back and Neck Procedures Except Spinal Fusion without CC/MCCSurgical1.55602.1+4.2%
521Hip Replacement with Principal Diagnosis of Hip Fracture with MCCSurgical2.85205.9-0.6%
522Hip Replacement with Principal Diagnosis of Hip Fracture without MCCSurgical2.11604.0-0.1%
523Extensive or Complex Spinal Fusion Procedures Except Cervical with MCCSurgical13.73809.2new
524Extensive or Complex Spinal Fusion Procedures Except Cervical with CCSurgical9.83205.6new
525Extensive or Complex Spinal Fusion Procedures Except Cervical without CC/MCCSurgical7.29503.2new
533Fractures of Femur with MCCMedical1.46404.2-6.6%
534Fractures of Femur without MCCMedical0.84003.0+4.2%
535Fractures of Hip and Pelvis with MCCMedical1.27203.9-0.8%
536Fractures of Hip and Pelvis without MCCMedical0.80702.9-0.1%
537Sprains, Strains, and Dislocations of Hip, Pelvis and Thigh with CC/MCCMedical0.91503.1-4.1%
538Sprains, Strains, and Dislocations of Hip, Pelvis and Thigh without CC/MCCMedical0.71202.4-1.1%
539Osteomyelitis with MCCMedical1.93806.1-1.6%
540Osteomyelitis with CCMedical1.30804.3+0.9%
541Osteomyelitis without CC/MCCMedical0.82902.8+5.3%
542Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with MCCMedical1.72104.9-2.6%
543Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CCMedical1.00603.4-2.1%
544Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy without CC/MCCMedical0.74002.7-2.0%
545Connective Tissue Disorders with MCCMedical2.39005.3-3.7%
546Connective Tissue Disorders with CCMedical1.17303.3+1.7%
547Connective Tissue Disorders without CC/MCCMedical0.75302.3-9.9%
548Septic Arthritis with MCCMedical1.95106.0+1.0%
549Septic Arthritis with CCMedical1.14303.7-5.3%
550Septic Arthritis without CC/MCCMedical0.86002.8-1.6%
551Medical Back Problems with MCCMedical1.63504.4-2.5%
552Medical Back Problems without MCCMedical0.95802.9-0.3%
553Bone Diseases and Arthropathies with MCCMedical1.24903.9-3.6%
554Bone Diseases and Arthropathies without MCCMedical0.83302.8+0.4%
555Signs and Symptoms of Musculoskeletal System and Connective Tissue with MCCMedical1.29103.7-2.3%
556Signs and Symptoms of Musculoskeletal System and Connective Tissue without MCCMedical0.82102.7-1.2%
557Tendonitis, Myositis and Bursitis with MCCMedical1.48804.6+0.1%
558Tendonitis, Myositis and Bursitis without MCCMedical0.88703.1-0.7%
559Aftercare, Musculoskeletal System and Connective Tissue with MCCMedical1.80904.9-3.0%
560Aftercare, Musculoskeletal System and Connective Tissue with CCMedical1.12303.8-0.3%
561Aftercare, Musculoskeletal System and Connective Tissue without CC/MCCMedical0.82603.0+2.7%
562Fracture, Sprain, Strain and Dislocation Except Femur, Hip, Pelvis and Thigh with MCCMedical1.39804.1-1.9%
563Fracture, Sprain, Strain and Dislocation Except Femur, Hip, Pelvis and Thigh without MCCMedical0.89803.0+0.3%
564Other Musculoskeletal System and Connective Tissue Diagnoses with MCCMedical1.49104.6-3.4%
565Other Musculoskeletal System and Connective Tissue Diagnoses with CCMedical0.97803.3+0.4%
566Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCCMedical0.73702.4-1.6%

How to read this table

The relative weight is the payment multiplier CMS applies to a hospital's wage-adjusted standardized amount; a weight of 2.0 pays roughly twice an average inpatient case before outliers and add-ons. Geometric mean length of stay is the figure used in post-acute transfer calculations, so stays shorter than it in a transfer DRG are paid per diem. The change column compares the FY2027 final weight with FY2026; moves larger than two percent usually come from code reassignments in the final rule's Table 6 series or from updated cost data, and are worth re-checking in contract models and budgets before October 1. Surgical DRGs require a qualifying operating-room procedure; medical DRGs are reached when no such procedure is coded.

Frequently asked questions

How many MS-DRGs are in MDC 08?

106 MS-DRGs are assigned to MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue) in the FY2027 v44 grouper: 72 surgical and 34 medical.

Which MDC 08 DRG has the highest weight?

DRG 523, Extensive or Complex Spinal Fusion Procedures Except Cervical with MCC, carries the highest FY2027 relative weight in this category at 13.7380; the lowest is DRG 538 at 0.7120.

How is a stay assigned to this MDC?

The grouper maps the principal diagnosis to MDC 08, then checks for a qualifying operating-room procedure to choose between the surgical and medical DRG partitions, and finally applies CC/MCC severity splits.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

Operational reference compiled from CMS publications. Relative weights are national factors; actual payment depends on hospital-specific rates and adjustments. Not legal, clinical or billing advice.