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MS-DRG 722 · MDC 12 · Medical

MS-DRG 722: Malignancy, Male Reproductive System with MCC

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: IPPS Table 5 FY2027 final rule (effective October 1, 2026); Definitions Manual v44 (effective October 1, 2026). Next CMS release: April 1, 2027 (v44.1 mid-year update), then the FY2028 final rule in August 2027.

Key facts for DRG 722

FY2027 relative weight
1.6680
Higher than 51% of all MS-DRGs
Change vs FY2026
-7.9%
FY2026 weight 1.8100
Geometric mean LOS
4.8 days
Arithmetic mean 6.6 days
MDC
12
Assignment of Diagnosis Codes
Severity level
with MCC (major complication or comorbidity)
Transfer policy
Not a transfer DRG

TL;DR

MS-DRG 722 is a medical group in MDC 12 (Assignment of Diagnosis Codes) at the highest-severity level of its family. CMS assigns it a FY2027 relative weight of 1.6680 with a geometric mean length of stay of 4.8 days and an arithmetic mean of 6.6. Its weight moved down 7.9% from FY2026 (1.8100). That weight is higher than 51% of all medical and surgical MS-DRGs. Its CC/MCC family (DRG 723, DRG 724) spans weights 0.5900 to 1.6680. The v44 Definitions Manual assigns it through 38 principal diagnosis codes.

What changed from FY2026 to FY2027

CMS recalibrates every MS-DRG weight annually from the prior year's MedPAR claims. For DRG 722 the FY2027 relative weight is 1.6680 against 1.8100 in FY2026, a fall of 7.85%, which exceeds the 2% threshold worth re-checking in contract models.

FY2026 versus FY2027 payment factors for MS-DRG 722
MetricFY2026FY2027Change
Relative weight1.81001.6680-0.1420
Geometric mean LOS (days)5.04.8-0.2
Arithmetic mean LOS (days)7.16.6-0.5
Weights shown are the FY2027 final values after the 10% cap on year-over-year reductions where applicable.

CC and MCC family

DRG 722 shares its base definition with 2 other MS-DRGs split by severity. The family's weights span 0.5900 to 1.6680, a 2.83× spread, which is the payment effect of documenting qualifying complications and comorbidities.

MS-DRGs in the same base group as DRG 722
DRGTitleFY2027 weightGMLOS
722Malignancy, Male Reproductive System with MCC1.66804.8
723Malignancy, Male Reproductive System with CC1.06903.3
724Malignancy, Male Reproductive System without CC/MCC0.59001.8

Grouper logic (v44 Definitions Manual)

Principal Diagnosis: 38 ICD-10 codes drive assignment to this group; the first 12 are shown.

Principal Diagnosis codes assigned to DRG 722 (sample)
ICD-10 codeDescription
C600Malignant neoplasm of prepuce
C601Malignant neoplasm of glans penis
C602Malignant neoplasm of body of penis
C608Malignant neoplasm of overlapping sites of penis
C609Malignant neoplasm of penis, unspecified
C61Malignant neoplasm of prostate
C6200Malignant neoplasm of unspecified undescended testis
C6201Malignant neoplasm of undescended right testis
C6202Malignant neoplasm of undescended left testis
C6210Malignant neoplasm of unspecified descended testis
C6211Malignant neoplasm of descended right testis
C6212Malignant neoplasm of descended left testis

Documentation and denial exposure

As a medical DRG, assignment depends on the principal diagnosis sequenced from the attending's documentation; a secondary condition sequenced first, or a symptom code in place of the confirmed diagnosis, changes the MDC or the DRG. Because this family splits by severity, auditors target CC and MCC capture: each secondary diagnosis must be documented as present, monitored, evaluated or treated during the stay to survive a DRG-validation review. Typical inpatient denial codes for this group: CARC 16 (claim lacks information needed to group the stay), CARC 50 (the admission or procedure is judged not medically necessary), CARC 97 (a service is bundled into the DRG payment).

How QuickIntell uses DRG 722 data

QuickCode groups inpatient encounters against the current v44 logic, flags CC and MCC candidates that lack supporting documentation, and shows the weight difference across the family before the claim drops. QuickScribe captures the attending's language that supports severity, and QuickRCM works DRG-validation denials with the grouper evidence attached.

Frequently asked questions — DRG 722

What is MS-DRG 722?

MS-DRG 722 is "Malignancy, Male Reproductive System with MCC", a medical Medicare Severity Diagnosis-Related Group in MDC 12, Assignment of Diagnosis Codes. Medicare pays inpatient stays grouped here at the hospital's base rate multiplied by the DRG relative weight.

What is the FY2027 relative weight for DRG 722?

The FY2027 relative weight is 1.6680 (IPPS final rule Table 5, effective October 1, 2026). In FY2026 it was 1.8100, a change of -7.9%.

What is the average length of stay for DRG 722?

CMS reports a geometric mean length of stay of 4.8 days and an arithmetic mean of 6.6 days for FY2027. The geometric mean is used for transfer-payment calculations.

Which DRGs are in the same CC/MCC family as 722?

DRG 723 (Malignancy, Male Reproductive System with CC, weight 1.0690); DRG 724 (Malignancy, Male Reproductive System without CC/MCC, weight 0.5900). The family's weights range from 0.5900 to 1.6680, so documented complications and comorbidities change payment materially.

What documentation supports the severity level of DRG 722?

DRG 722 requires at least one secondary diagnosis on the CMS Major Complication or Comorbidity list, documented as present and clinically addressed during the stay (monitored, evaluated, treated or extending the stay). Conditions such as acute respiratory failure, severe sepsis or acute kidney injury with specified cause qualify only when the attending's note states the diagnosis itself, not just the lab values. Recovery auditors downgrade this group to the CC or base level when the MCC rests on an unconfirmed query or a resolved historical condition, so the query response and the discharge summary must agree.

Which codes group to DRG 722?

The v44 Definitions Manual lists 38 principal diagnosis codes for this group. Examples from the principal diagnosis list: C600 (Malignant neoplasm of prepuce); C601 (Malignant neoplasm of glans penis); C602 (Malignant neoplasm of body of penis); C608 (Malignant neoplasm of overlapping sites of penis).

Is DRG 722 a post-acute transfer DRG?

No. DRG 722 is not on the FY2027 post-acute care transfer list, so the transfer per-diem policy does not apply to it.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from the CMS IPPS FY2027 final rule (Table 5) and the v44 ICD-10 MS-DRG Definitions Manual. Relative weights are national factors; actual payment depends on each hospital's wage-adjusted base rate, add-ons, outliers and transfer adjustments. Nothing here is legal, clinical or billing advice; verify grouping against your encoder and the published CMS files.