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ICD-10-CM codes for Hyperlipidemia

The ICD-10-CM Index to Diseases lists hyperlipidemia under "Hyperlipemia, hyperlipidemia". Without more detail in the record it is coded E78.5, hyperlipidemia, unspecified, in tabular category E78 (Disorders of lipoprotein metabolism and other lipidemias). More specific documentation changes the code, for example combined: E78.2; combined, familial: E78.49; group, A: E78.00.

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: ICD-10-CM code descriptions: FY2027 (effective October 1, 2026). Next CMS release: FY2028 code files, effective October 1, 2027.

Default code: E78.5 Hyperlipidemia, unspecified

Index to Diseases entry: Hyperlipemia, hyperlipidemia

Each row is a subterm under the entry. Indented rows refine the row above; “see” sends you to another entry. Look the code up in the tabular list before reporting it: the tabular notes can require a more specific or an additional code.

ICD-10-CM index subterms under "Hyperlipemia, hyperlipidemia"
DocumentationCodeCode description or cross-reference
combinedE78.2Mixed hyperlipidemia
familialE78.49Other hyperlipidemia
group—
AE78.00Pure hypercholesterolemia, unspecified
BE78.1Pure hyperglyceridemia
CE78.2Mixed hyperlipidemia
DE78.3Hyperchylomicronemia
mixedE78.2Mixed hyperlipidemia
specified NECE78.49Other hyperlipidemia

How to read an Index to Diseases entry

  • Words in parentheses after a term are nonessential modifiers: they may or may not appear in the record, and they do not change the code.
  • Indented subterms are essential modifiers. Each one describes a different site, type or cause, and when the record supports it, the subterm's code replaces the default code.
  • “With” and “in” link two conditions. The Official Guidelines presume a causal relationship between conditions linked by “with” in the index unless the provider documents that they are unrelated.
  • “See” sends you to another entry that holds the code; “see also” points to another entry that may be useful.
  • A code that ends in a dash, such as I50.-, is incomplete: the tabular list gives the characters it still needs.
  • Never report a code from the index alone. Find it in the tabular list and apply its includes, excludes, code first, use additional code and 7th-character instructions before you report it.

Once the code is settled, check what it does for payment: the HCC lookup for risk adjustment, the CC/MCC exclusion check for inpatient severity, and the LCD code lookup for local coverage of the service it supports. The guide to ICD-10 diagnosis codes explains the code structure.

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Frequently asked questions

What is the ICD-10 code for hyperlipidemia?

E78.5 (Hyperlipidemia, unspecified) is the code the index assigns to "Hyperlipemia, hyperlipidemia" with no further detail. Confirm it in the tabular list before reporting it, because the tabular notes can require a different or additional code.

Which documentation changes the code for hyperlipidemia?

The index lists 8 subterms with their own codes, including combined (E78.2); combined familial (E78.49); group A (E78.00); group B (E78.1); group C (E78.2).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

The entry, subterms and codes are reproduced from the FY2027 ICD-10-CM index; code descriptions are from the FY2027 code files. Code from the medical record using both the index and the tabular list, under the ICD-10-CM Official Guidelines. Not legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.