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HCPCS J7212 · Level II · Part B drug

HCPCS J7212: Factor viia (antihemophilic factor, recombinant)-jncw (sevenfact), 1 microgram

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: ASP payment limits October 2026 (effective October 1, 2026); MUE and NCCI edits 2026 Q4 (effective October 1, 2026); OPPS Addendum B July 2026 (effective July 1, 2026). Next CMS release: January 1, 2027 (ASP, MUE, NCCI and OPPS quarterly updates).

Key facts for J7212

Billing unit
1 MCG
Factor viia recomb sevenfact
ASP payment limit
$2.25
October 2026; +2.6% vs July 2026
Practitioner MUE
90000
MAI 1
OPPS status
SI K
APC 9395
NCCI exposure
no PTP pairs
Coverage articles
1
7 states

TL;DR

HCPCS J7212 is the Level II code for Factor viia (antihemophilic factor, recombinant)-jncw (sevenfact), 1 microgram, billed per 1 MCG. The Medicare Part B ASP payment limit for October 2026 is $2.25 per billing unit, up 2.6% from July 2026. The practitioner MUE allows up to 90000 units per date of service (MAI 1). Under OPPS it carries status indicator K in APC 9395. J7212 is billed in units of 1 MCG; the quantity administered, the NDC package and the units on the claim must reconcile, which is the check that prevents CARC 16 and 151 returns on this line. The ASP crosswalk maps 3 NDCs to it, sold as Sevenfact by Hema Biologics. 1 Medicare coverage article lists the code across 7 states, including .

Medicare Part B payment limit (ASP)

CMS sets the Part B payment limit for J7212 at $2.25 per 1 MCG for October 2026, derived from manufacturer average sales price plus 6%, compared with $2.194 in July 2026. Beneficiary coinsurance is 20%.

ASP payment limits for J7212
QuarterPayment limitPerCoinsurance
October 2026$2.251 MCG20%
July 2026$2.1941 MCG—
Source: CMS Medicare Part B Drug Payment Limit File. Commercial and Medicaid payers set their own rates.

NDC to HCPCS billing-unit conversion

The October 2026 ASP crosswalk maps 3 NDCs from 1 labeler to J7212. Report the NDC in the claim's drug segment and bill the number of J7212 units that equals the quantity administered divided by 1 MCG; the last column gives units per full package.

NDCs that crosswalk to J7212
NDCDrug nameLabelerPackage sizeBilling units / package
71127-1000-01SevenfactHema Biologics1 × 11000
71127-2000-01SevenfactHema Biologics1 × 12000
71127-5000-01SevenfactHema Biologics1 × 15000

Medically Unlikely Edits (MUE)

CMS publishes 2 MUE values for J7212. For practitioners the limit is 90000 units per date of service with adjudication indicator 1, a claim-line edit: units above the limit deny on that line, and documented separate services can be reported on another line with an appropriate modifier.

MUE values for J7212 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services900001 Line EditPrescribing Information
Facility outpatient hospital900001 Line EditPrescribing Information

NCCI edits and add-on relationships

No active practitioner PTP pair lists J7212 as a column-1 or column-2 code in v323r0. Drug supply codes are rarely bundled; the administration codes billed with them are where PTP edits usually apply.

J7212 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Medicare coverage articles

1 current Medicare Administrative Contractor article lists J7212 in their HCPCS tables, covering 7 states. Each article carries the covered and non-covered ICD-10 codes that medical-necessity denials (CARC 50) are adjudicated against.

Billing and Coding Articles listing J7212
ArticleTitleContractor(s)StatesRelated LCD
Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3Palmetto GBAAL GA NC SC TN VA WV—

Hospital outpatient (OPPS) status

In the July 2026 OPPS Addendum B, J7212 carries status indicator K and is assigned to APC 9395, with a published national unadjusted payment of $2.19. Status K means the drug is paid separately under OPPS at the ASP-based rate rather than packaged into the procedure.

Common denials for J7212 and how to prevent them

CARC 16 · M119

NDC missing, invalid or not matched to the HCPCS code

CARC 151 · N362

units billed exceed the MUE for the date of service

CARC 50 · N115

diagnosis not covered by the applicable coverage article or LCD

How QuickIntell checks J7212 before the claim leaves

QuickCode validates the NDC-to-unit conversion against the current ASP crosswalk, checks units against every published MUE setting and flags PTP and add-on conflicts on the same claim. QuickRCM routes CARC 16, 151 and 50 denials on drug lines with the matching coverage article attached so the appeal starts with evidence.

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Frequently asked questions — HCPCS J7212

What does HCPCS code J7212 describe?

J7212 is defined by CMS as "Factor viia (antihemophilic factor, recombinant)-jncw (sevenfact), 1 microgram". Each billing unit represents 1 MCG, so the units reported on the claim must equal the dose administered divided by that unit.

What is the Medicare reimbursement for J7212 in October 2026?

The ASP-based payment limit is $2.25 per 1 MCG, with 20% beneficiary coinsurance. Medicare Administrative Contractors apply this limit; commercial payers use their own fee schedules. The July 2026 limit was $2.194.

How many units of J7212 can be billed per day?

The practitioner Medically Unlikely Edit is 90000 units per date of service with adjudication indicator 1 (1 Line Edit). MAI 1 edits apply per claim line; units may be split across lines with an appropriate modifier when justified. CMS cites "Prescribing Information" as the rationale.

Which NDCs map to J7212?

The October 2026 ASP crosswalk lists 3 NDCs from 1 labeler: Sevenfact (Hema Biologics). For example NDC 71127-1000-01 is a 1 package equal to 1000 billing units. The crosswalk's billing-units-per-package figure converts each package into J7212 units.

Does J7212 have NCCI bundling edits?

No active practitioner PTP pairs list J7212 as a column-1 or column-2 code in the v323r0 release. Unit limits (MUE) and medical-necessity coverage rules still apply.

Which Medicare coverage articles mention J7212?

1 current Billing and Coding Article in the Medicare Coverage Database list J7212, covering 7 states: (Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from CMS publications: the Medicare Part B drug payment limit and NDC crosswalk files, NCCI MUE and add-on edit tables, aggregate PTP statistics, OPPS Addendum B and the Medicare Coverage Database. Payment limits are Medicare national amounts; commercial and Medicaid payers differ. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.