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HCPCS J7207 · Level II · Part B drug

HCPCS J7207: Injection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u.

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: ASP payment limits October 2026 (effective October 1, 2026); MUE and NCCI edits 2026 Q4 (effective October 1, 2026); OPPS Addendum B July 2026 (effective July 1, 2026). Next CMS release: January 1, 2027 (ASP, MUE, NCCI and OPPS quarterly updates).

Key facts for J7207

Billing unit
1 IU
Factor viii pegylated recomb
ASP payment limit
$2.185
October 2026; +3.1% vs July 2026
Practitioner MUE
22500
MAI 1
OPPS status
SI K
APC 1844
NCCI exposure
no PTP pairs
Coverage articles
1
7 states

TL;DR

HCPCS J7207 is the Level II code for Injection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u., billed per 1 IU. The Medicare Part B ASP payment limit for October 2026 is $2.185 per billing unit, up 3.1% from July 2026. The practitioner MUE allows up to 22500 units per date of service (MAI 1). Under OPPS it carries status indicator K in APC 1844. J7207 is billed in units of 1 IU; the quantity administered, the NDC package and the units on the claim must reconcile, which is the check that prevents CARC 16 and 151 returns on this line. The ASP crosswalk maps 7 NDCs to it, sold as Adynovate by Takeda Pharmaceuticals America, Inc.. 1 Medicare coverage article lists the code across 7 states, including .

Medicare Part B payment limit (ASP)

CMS sets the Part B payment limit for J7207 at $2.185 per 1 IU for October 2026, derived from manufacturer average sales price plus 6%, compared with $2.119 in July 2026. Beneficiary coinsurance is 20%.

ASP payment limits for J7207
QuarterPayment limitPerCoinsurance
October 2026$2.1851 IU20%
July 2026$2.1191 IU—
Source: CMS Medicare Part B Drug Payment Limit File. Commercial and Medicaid payers set their own rates.

NDC to HCPCS billing-unit conversion

The October 2026 ASP crosswalk maps 7 NDCs from 1 labeler to J7207. Report the NDC in the claim's drug segment and bill the number of J7207 units that equals the quantity administered divided by 1 IU; the last column gives units per full package.

NDCs that crosswalk to J7207
NDCDrug nameLabelerPackage sizeBilling units / package
00944-4622-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4623-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4624-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4625-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4626-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4627-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11
00944-4628-01AdynovateTakeda Pharmaceuticals America, Inc.1 × 11

Medically Unlikely Edits (MUE)

CMS publishes 2 MUE values for J7207. For practitioners the limit is 22500 units per date of service with adjudication indicator 1, a claim-line edit: units above the limit deny on that line, and documented separate services can be reported on another line with an appropriate modifier.

MUE values for J7207 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services225001 Line EditPrescribing Information
Facility outpatient hospital225001 Line EditPrescribing Information

NCCI edits and add-on relationships

No active practitioner PTP pair lists J7207 as a column-1 or column-2 code in v323r0. Drug supply codes are rarely bundled; the administration codes billed with them are where PTP edits usually apply.

J7207 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Medicare coverage articles

1 current Medicare Administrative Contractor article lists J7207 in their HCPCS tables, covering 7 states. Each article carries the covered and non-covered ICD-10 codes that medical-necessity denials (CARC 50) are adjudicated against.

Billing and Coding Articles listing J7207
ArticleTitleContractor(s)StatesRelated LCD
Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3Palmetto GBAAL GA NC SC TN VA WV—

Hospital outpatient (OPPS) status

In the July 2026 OPPS Addendum B, J7207 carries status indicator K and is assigned to APC 1844, with a published national unadjusted payment of $2.12. Status K means the drug is paid separately under OPPS at the ASP-based rate rather than packaged into the procedure.

Common denials for J7207 and how to prevent them

CARC 16 · M119

NDC missing, invalid or not matched to the HCPCS code

CARC 151 · N362

units billed exceed the MUE for the date of service

CARC 50 · N115

diagnosis not covered by the applicable coverage article or LCD

How QuickIntell checks J7207 before the claim leaves

QuickCode validates the NDC-to-unit conversion against the current ASP crosswalk, checks units against every published MUE setting and flags PTP and add-on conflicts on the same claim. QuickRCM routes CARC 16, 151 and 50 denials on drug lines with the matching coverage article attached so the appeal starts with evidence.

Explore QuickCodeExplore QuickRCMBook a demo

Frequently asked questions — HCPCS J7207

What does HCPCS code J7207 describe?

J7207 is defined by CMS as "Injection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u.". Each billing unit represents 1 IU, so the units reported on the claim must equal the dose administered divided by that unit.

What is the Medicare reimbursement for J7207 in October 2026?

The ASP-based payment limit is $2.185 per 1 IU, with 20% beneficiary coinsurance. Medicare Administrative Contractors apply this limit; commercial payers use their own fee schedules. The July 2026 limit was $2.119.

How many units of J7207 can be billed per day?

The practitioner Medically Unlikely Edit is 22500 units per date of service with adjudication indicator 1 (1 Line Edit). MAI 1 edits apply per claim line; units may be split across lines with an appropriate modifier when justified. CMS cites "Prescribing Information" as the rationale.

Which NDCs map to J7207?

The October 2026 ASP crosswalk lists 7 NDCs from 1 labeler: Adynovate (Takeda Pharmaceuticals America, Inc.). For example NDC 00944-4622-01 is a 1 package equal to 1 billing unit. The crosswalk's billing-units-per-package figure converts each package into J7207 units.

Does J7207 have NCCI bundling edits?

No active practitioner PTP pairs list J7207 as a column-1 or column-2 code in the v323r0 release. Unit limits (MUE) and medical-necessity coverage rules still apply.

Which Medicare coverage articles mention J7207?

1 current Billing and Coding Article in the Medicare Coverage Database list J7207, covering 7 states: (Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from CMS publications: the Medicare Part B drug payment limit and NDC crosswalk files, NCCI MUE and add-on edit tables, aggregate PTP statistics, OPPS Addendum B and the Medicare Coverage Database. Payment limits are Medicare national amounts; commercial and Medicaid payers differ. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.