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HCPCS J1626 · Level II · Part B drug

HCPCS J1626: Injection, granisetron hydrochloride, 100 mcg

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: ASP payment limits October 2026 (effective October 1, 2026); MUE and NCCI edits 2026 Q4 (effective October 1, 2026); OPPS Addendum B July 2026 (effective July 1, 2026). Next CMS release: January 1, 2027 (ASP, MUE, NCCI and OPPS quarterly updates).

Key facts for J1626

Billing unit
100 MCG
Granisetron hcl injection
ASP payment limit
$0.16
October 2026; -19.6% vs July 2026
Practitioner MUE
30
MAI 3
OPPS status
SI N
NCCI exposure
no PTP pairs
Coverage articles
0
none list this code

TL;DR

HCPCS J1626 is the Level II code for Injection, granisetron hydrochloride, 100 mcg, billed per 100 MCG. The Medicare Part B ASP payment limit for October 2026 is $0.16 per billing unit, down 19.6% from July 2026. The practitioner MUE allows up to 30 units per date of service (MAI 3). Under OPPS it carries status indicator N. J1626 is billed in units of 100 MCG; the quantity administered, the NDC package and the units on the claim must reconcile, which is the check that prevents CARC 16 and 151 returns on this line. The ASP crosswalk maps 5 NDCs to it, sold as Granisetron HCl by Hikma Pharmaceuticals USA Inc., FreseniUS Kabi USA, LLC, Mylan Institutional LLC. No current Billing and Coding Article lists J1626, so coverage follows the FDA label, compendia and any applicable NCD.

Medicare Part B payment limit (ASP)

CMS sets the Part B payment limit for J1626 at $0.16 per 100 MCG for October 2026, derived from manufacturer average sales price plus 6%, compared with $0.199 in July 2026. Beneficiary coinsurance is 20%.

ASP payment limits for J1626
QuarterPayment limitPerCoinsurance
October 2026$0.16100 MCG20%
July 2026$0.199100 MCG—
Source: CMS Medicare Part B Drug Payment Limit File. Commercial and Medicaid payers set their own rates.

NDC to HCPCS billing-unit conversion

The October 2026 ASP crosswalk maps 5 NDCs from 3 labelers to J1626. Report the NDC in the claim's drug segment and bill the number of J1626 units that equals the quantity administered divided by 100 MCG; the last column gives units per full package.

NDCs that crosswalk to J1626
NDCDrug nameLabelerPackage sizeBilling units / package
00143-9744-10Granisetron HClHikma Pharmaceuticals USA Inc.1 × 10100
00143-9745-05Granisetron HClHikma Pharmaceuticals USA Inc.4 × 5200
63323-0318-01Granisetron HClFreseniUS Kabi USA, LLC1 × 110
67457-0863-01Granisetron HClMylan Institutional LLC1 × 110
67457-0864-04Granisetron HClMylan Institutional LLC4 × 140

Medically Unlikely Edits (MUE)

CMS publishes 3 MUE values for J1626. For practitioners the limit is 30 units per date of service with adjudication indicator 3, a date-of-service clinical edit: units above the limit deny but can be paid on appeal with documentation that the quantity was medically reasonable.

MUE values for J1626 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services303 Date of Service Edit: ClinicalClinical: Data
Facility outpatient hospital303 Date of Service Edit: ClinicalClinical: Data
DME supplier03 Date of Service Edit: ClinicalCMS Policy

NCCI edits and add-on relationships

No active practitioner PTP pair lists J1626 as a column-1 or column-2 code in v323r0. Drug supply codes are rarely bundled; the administration codes billed with them are where PTP edits usually apply.

J1626 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Medicare coverage articles

No current Billing and Coding Article lists J1626 in its HCPCS table. Coverage then follows the drug's FDA label, compendia and any National Coverage Determination; check the Medicare Coverage Database before administering off-label.

Hospital outpatient (OPPS) status

In the July 2026 OPPS Addendum B, J1626 carries status indicator N. Status N means payment is packaged into the associated procedure and no separate OPPS payment is made.

Common denials for J1626 and how to prevent them

CARC 16 · M119

NDC missing, invalid or not matched to the HCPCS code

CARC 151 · N362

units billed exceed the MUE for the date of service

CARC 50 · N115

diagnosis not covered by the applicable coverage article or LCD

How QuickIntell checks J1626 before the claim leaves

QuickCode validates the NDC-to-unit conversion against the current ASP crosswalk, checks units against every published MUE setting and flags PTP and add-on conflicts on the same claim. QuickRCM routes CARC 16, 151 and 50 denials on drug lines with the matching coverage article attached so the appeal starts with evidence.

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Frequently asked questions — HCPCS J1626

What does HCPCS code J1626 describe?

J1626 is defined by CMS as "Injection, granisetron hydrochloride, 100 mcg". Each billing unit represents 100 MCG, so the units reported on the claim must equal the dose administered divided by that unit.

What is the Medicare reimbursement for J1626 in October 2026?

The ASP-based payment limit is $0.16 per 100 MCG, with 20% beneficiary coinsurance. Medicare Administrative Contractors apply this limit; commercial payers use their own fee schedules. The July 2026 limit was $0.199.

How many units of J1626 can be billed per day?

The practitioner Medically Unlikely Edit is 30 units per date of service with adjudication indicator 3 (3 Date of Service Edit: Clinical). MAI 3 edits can be appealed with documentation that the units were medically reasonable. CMS cites "Clinical: Data" as the rationale.

Which NDCs map to J1626?

The October 2026 ASP crosswalk lists 5 NDCs from 3 labelers: Granisetron HCl (Hikma Pharmaceuticals USA Inc.); Granisetron HCl (FreseniUS Kabi USA, LLC); Granisetron HCl (Mylan Institutional LLC). For example NDC 00143-9744-10 is a 1 package equal to 100 billing units. The crosswalk's billing-units-per-package figure converts each package into J1626 units.

Does J1626 have NCCI bundling edits?

No active practitioner PTP pairs list J1626 as a column-1 or column-2 code in the v323r0 release. Unit limits (MUE) and medical-necessity coverage rules still apply.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from CMS publications: the Medicare Part B drug payment limit and NDC crosswalk files, NCCI MUE and add-on edit tables, aggregate PTP statistics, OPPS Addendum B and the Medicare Coverage Database. Payment limits are Medicare national amounts; commercial and Medicaid payers differ. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.