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HCPCS J0885 · Level II · Part B drug

HCPCS J0885: Injection, epoetin alfa, (for non-esrd use), 1000 units

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: ASP payment limits October 2026 (effective October 1, 2026); MUE and NCCI edits 2026 Q4 (effective October 1, 2026); OPPS Addendum B July 2026 (effective July 1, 2026). Next CMS release: January 1, 2027 (ASP, MUE, NCCI and OPPS quarterly updates).

Key facts for J0885

Billing unit
1000 UNITS
Epoetin alfa, non-esrd
ASP payment limit
$6.669
October 2026; -3.0% vs July 2026
Practitioner MUE
60
MAI 3
OPPS status
SI K
APC 1686
NCCI exposure
no PTP pairs
Coverage articles
1
2 states

TL;DR

HCPCS J0885 is the Level II code for Injection, epoetin alfa, (for non-esrd use), 1000 units, billed per 1000 UNITS. The Medicare Part B ASP payment limit for October 2026 is $6.669 per billing unit, down 3.0% from July 2026. The practitioner MUE allows up to 60 units per date of service (MAI 3). Under OPPS it carries status indicator K in APC 1686. The descriptor restricts this code to non-ESRD use; the ESRD-on-dialysis counterpart is a separate code and billing the wrong one is a frequent reason for CARC 16 returns. The ASP crosswalk maps 18 NDCs to it, sold as Epogen, Procrit by Amgen Inc, Janssen Products, LP. 1 Medicare coverage article lists the code across 2 states, including .

Medicare Part B payment limit (ASP)

CMS sets the Part B payment limit for J0885 at $6.669 per 1000 UNITS for October 2026, derived from manufacturer average sales price plus 6%, compared with $6.876 in July 2026. Beneficiary coinsurance is 20%.

ASP payment limits for J0885
QuarterPayment limitPerCoinsurance
October 2026$6.6691000 UNITS20%
July 2026$6.8761000 UNITS—
Source: CMS Medicare Part B Drug Payment Limit File. Commercial and Medicaid payers set their own rates.

NDC to HCPCS billing-unit conversion

The October 2026 ASP crosswalk maps 18 NDCs from 2 labelers to J0885. Report the NDC in the claim's drug segment and bill the number of J0885 units that equals the quantity administered divided by 1000 UNITS; the last column gives units per full package.

NDCs that crosswalk to J0885
NDCDrug nameLabelerPackage sizeBilling units / package
55513-0126-10EpogenAmgen Inc1 × 1020
55513-0126-20EpogenAmgen Inc1 × 1020
55513-0144-10EpogenAmgen Inc1 × 10100
55513-0148-10EpogenAmgen Inc1 × 1040
55513-0267-10EpogenAmgen Inc1 × 1030
55513-0267-20EpogenAmgen Inc1 × 1030
55513-0283-10EpogenAmgen Inc2 × 10200
55513-0283-20EpogenAmgen Inc2 × 10200
55513-0478-10EpogenAmgen Inc1 × 10200
55513-0478-20EpogenAmgen Inc1 × 10200
59676-0302-01ProcritJanssen Products, LP1 × 612
59676-0303-01ProcritJanssen Products, LP1 × 618
59676-0304-01ProcritJanssen Products, LP1 × 624
59676-0310-01ProcritJanssen Products, LP1 × 660
59676-0310-02ProcritJanssen Products, LP1 × 25250
59676-0312-04ProcritJanssen Products, LP2 × 480
59676-0320-04ProcritJanssen Products, LP1 × 480
59676-0340-01ProcritJanssen Products, LP1 × 4160

Medically Unlikely Edits (MUE)

CMS publishes 3 MUE values for J0885. For practitioners the limit is 60 units per date of service with adjudication indicator 3, a date-of-service clinical edit: units above the limit deny but can be paid on appeal with documentation that the quantity was medically reasonable.

MUE values for J0885 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services603 Date of Service Edit: ClinicalPrescribing Information
Facility outpatient hospital603 Date of Service Edit: ClinicalPrescribing Information
DME supplier03 Date of Service Edit: ClinicalCMS Policy

NCCI edits and add-on relationships

No active practitioner PTP pair lists J0885 as a column-1 or column-2 code in v323r0. Drug supply codes are rarely bundled; the administration codes billed with them are where PTP edits usually apply.

J0885 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Medicare coverage articles

1 current Medicare Administrative Contractor article lists J0885 in their HCPCS tables, covering 2 states. Each article carries the covered and non-covered ICD-10 codes that medical-necessity denials (CARC 50) are adjudicated against.

Billing and Coding Articles listing J0885
ArticleTitleContractor(s)StatesRelated LCD
Billing and Coding: Erythropoiesis Stimulating Agents (ESA)CGS Administrators, LLCKY OHL34356

Hospital outpatient (OPPS) status

In the July 2026 OPPS Addendum B, J0885 carries status indicator K and is assigned to APC 1686, with a published national unadjusted payment of $6.88. Status K means the drug is paid separately under OPPS at the ASP-based rate rather than packaged into the procedure.

Common denials for J0885 and how to prevent them

NDC missing, invalid or not matched to the HCPCS code

units billed exceed the MUE for the date of service

diagnosis not covered by the applicable coverage article or LCD

How QuickIntell checks J0885 before the claim leaves

QuickCode validates the NDC-to-unit conversion against the current ASP crosswalk, checks units against every published MUE setting and flags PTP and add-on conflicts on the same claim. QuickRCM routes CARC 16, 151 and 50 denials on drug lines with the matching coverage article attached so the appeal starts with evidence.

Frequently asked questions — HCPCS J0885

What does HCPCS code J0885 describe?

J0885 is defined by CMS as "Injection, epoetin alfa, (for non-esrd use), 1000 units". Each billing unit represents 1000 UNITS, so the units reported on the claim must equal the dose administered divided by that unit.

What is the Medicare reimbursement for J0885 in October 2026?

The ASP-based payment limit is $6.669 per 1000 UNITS, with 20% beneficiary coinsurance. Medicare Administrative Contractors apply this limit; commercial payers use their own fee schedules. The July 2026 limit was $6.876.

How many units of J0885 can be billed per day?

The practitioner Medically Unlikely Edit is 60 units per date of service with adjudication indicator 3 (3 Date of Service Edit: Clinical). MAI 3 edits can be appealed with documentation that the units were medically reasonable. CMS cites "Prescribing Information" as the rationale.

Which NDCs map to J0885?

The October 2026 ASP crosswalk lists 18 NDCs from 2 labelers: Epogen (Amgen Inc); Procrit (Janssen Products, LP). For example NDC 55513-0126-10 is a 1 package equal to 20 billing units. The crosswalk's billing-units-per-package figure converts each package into J0885 units.

Does J0885 have NCCI bundling edits?

No active practitioner PTP pairs list J0885 as a column-1 or column-2 code in the v323r0 release. Unit limits (MUE) and medical-necessity coverage rules still apply.

Which Medicare coverage articles mention J0885?

1 current Billing and Coding Article in the Medicare Coverage Database list J0885, covering 2 states: (Billing and Coding: Erythropoiesis Stimulating Agents (ESA)).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from CMS publications: the Medicare Part B drug payment limit and NDC crosswalk files, NCCI MUE and add-on edit tables, aggregate PTP statistics, OPPS Addendum B and the Medicare Coverage Database. Payment limits are Medicare national amounts; commercial and Medicaid payers differ. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.