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HCPCS J0840 · Level II · Part B drug

HCPCS J0840: Injection, crotalidae polyvalent immune fab (ovine), up to 1 gram

Reviewed by QuickIntell RCM Editorial Team · Last reviewed

Data effective
Data currency: ASP payment limits October 2026 (effective October 1, 2026); MUE and NCCI edits 2026 Q4 (effective October 1, 2026); OPPS Addendum B July 2026 (effective July 1, 2026). Next CMS release: January 1, 2027 (ASP, MUE, NCCI and OPPS quarterly updates).

Key facts for J0840

Billing unit
UP TO 1 GM
Crotalidae poly immune fab
ASP payment limit
$2,044.383
October 2026; +7.2% vs July 2026
Practitioner MUE
6
MAI 3
OPPS status
SI K
APC 9274
NCCI exposure
no PTP pairs
Coverage articles
1
4 states

TL;DR

HCPCS J0840 is the Level II code for Injection, crotalidae polyvalent immune fab (ovine), up to 1 gram, billed per UP TO 1 GM. The Medicare Part B ASP payment limit for October 2026 is $2,044.383 per billing unit, up 7.2% from July 2026. The practitioner MUE allows up to 6 units per date of service (MAI 3). Under OPPS it carries status indicator K in APC 9274. J0840 is billed in units of UP TO 1 GM; the quantity administered, the NDC package and the units on the claim must reconcile, which is the check that prevents CARC 16 and 151 returns on this line. The ASP crosswalk maps 1 NDC to it, sold as Crofab by BTG International Inc.. 1 Medicare coverage article lists the code across 4 states, including .

Medicare Part B payment limit (ASP)

CMS sets the Part B payment limit for J0840 at $2,044.383 per UP TO 1 GM for October 2026, derived from manufacturer average sales price plus 6%, compared with $1,906.906 in July 2026. Beneficiary coinsurance is 20%.

ASP payment limits for J0840
QuarterPayment limitPerCoinsurance
October 2026$2,044.383UP TO 1 GM20%
July 2026$1,906.906UP TO 1 GM—
Source: CMS Medicare Part B Drug Payment Limit File. Commercial and Medicaid payers set their own rates.

NDC to HCPCS billing-unit conversion

The October 2026 ASP crosswalk maps 1 NDC from 1 labeler to J0840. Report the NDC in the claim's drug segment and bill the number of J0840 units that equals the quantity administered divided by UP TO 1 GM; the last column gives units per full package.

NDCs that crosswalk to J0840
NDCDrug nameLabelerPackage sizeBilling units / package
50633-0110-12CrofabBTG International Inc.1 × 22

Medically Unlikely Edits (MUE)

CMS publishes 3 MUE values for J0840. For practitioners the limit is 6 units per date of service with adjudication indicator 3, a date-of-service clinical edit: units above the limit deny but can be paid on appeal with documentation that the quantity was medically reasonable.

MUE values for J0840 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services63 Date of Service Edit: ClinicalClinical: CMS Workgroup
Facility outpatient hospital183 Date of Service Edit: ClinicalPrescribing Information
DME supplier03 Date of Service Edit: ClinicalCMS Policy

NCCI edits and add-on relationships

No active practitioner PTP pair lists J0840 as a column-1 or column-2 code in v323r0. Drug supply codes are rarely bundled; the administration codes billed with them are where PTP edits usually apply.

J0840 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Medicare coverage articles

1 current Medicare Administrative Contractor article lists J0840 in their HCPCS tables, covering 4 states. Each article carries the covered and non-covered ICD-10 codes that medical-necessity denials (CARC 50) are adjudicated against.

Billing and Coding Articles listing J0840
ArticleTitleContractor(s)StatesRelated LCD
Billing and Coding: Immune GlobulinsWisconsin Physicians Service Insurance CorporationIA KS MO NEL34771

Hospital outpatient (OPPS) status

In the July 2026 OPPS Addendum B, J0840 carries status indicator K and is assigned to APC 9274, with a published national unadjusted payment of $1,906.91. Status K means the drug is paid separately under OPPS at the ASP-based rate rather than packaged into the procedure.

Common denials for J0840 and how to prevent them

CARC 16 · M119

NDC missing, invalid or not matched to the HCPCS code

CARC 151 · N362

units billed exceed the MUE for the date of service

CARC 50 · N115

diagnosis not covered by the applicable coverage article or LCD

How QuickIntell checks J0840 before the claim leaves

QuickCode validates the NDC-to-unit conversion against the current ASP crosswalk, checks units against every published MUE setting and flags PTP and add-on conflicts on the same claim. QuickRCM routes CARC 16, 151 and 50 denials on drug lines with the matching coverage article attached so the appeal starts with evidence.

Explore QuickCodeExplore QuickRCMBook a demo

Frequently asked questions — HCPCS J0840

What does HCPCS code J0840 describe?

J0840 is defined by CMS as "Injection, crotalidae polyvalent immune fab (ovine), up to 1 gram". Each billing unit represents UP TO 1 GM, so the units reported on the claim must equal the dose administered divided by that unit.

What is the Medicare reimbursement for J0840 in October 2026?

The ASP-based payment limit is $2,044.383 per UP TO 1 GM, with 20% beneficiary coinsurance. Medicare Administrative Contractors apply this limit; commercial payers use their own fee schedules. The July 2026 limit was $1,906.906.

How many units of J0840 can be billed per day?

The practitioner Medically Unlikely Edit is 6 units per date of service with adjudication indicator 3 (3 Date of Service Edit: Clinical). MAI 3 edits can be appealed with documentation that the units were medically reasonable. CMS cites "Clinical: CMS Workgroup" as the rationale.

Which NDCs map to J0840?

The October 2026 ASP crosswalk lists 1 NDC from 1 labeler: Crofab (BTG International Inc.). For example NDC 50633-0110-12 is a 1 package equal to 2 billing units. The crosswalk's billing-units-per-package figure converts each package into J0840 units.

Does J0840 have NCCI bundling edits?

No active practitioner PTP pairs list J0840 as a column-1 or column-2 code in the v323r0 release. Unit limits (MUE) and medical-necessity coverage rules still apply.

Which Medicare coverage articles mention J0840?

1 current Billing and Coding Article in the Medicare Coverage Database list J0840, covering 4 states: (Billing and Coding: Immune Globulins).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-01. Verify against the primary file before billing or contracting decisions.

Disclaimer

This page is an operational reference compiled from CMS publications: the Medicare Part B drug payment limit and NDC crosswalk files, NCCI MUE and add-on edit tables, aggregate PTP statistics, OPPS Addendum B and the Medicare Coverage Database. Payment limits are Medicare national amounts; commercial and Medicaid payers differ. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.