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HCPCS G0105 · Level II · G code

G0105: Colorectal cancer screening; colonoscopy on individual at high risk, HCPCS Level II G code

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: HCPCS Level II file: October 2026 (effective October 1, 2026); PFS relative value file: RVU26D, released August 26, 2026 (effective October 1, 2026); NCCI MUE tables: 2026 Q4 (effective October 1, 2026); NCCI PTP edits: v323r0 (2026 Q4) (effective October 1, 2026); OPPS Addendum B: October 2026 (effective October 1, 2026); Medicare Coverage Database LCD export: MCD release October 8, 2026 (effective October 4, 2026). Next CMS release: January 1, 2027 (quarterly update) for the HCPCS Level II file and NCCI MUE tables and NCCI PTP edits and OPPS Addendum B; RVU27A with the CY2027 PFS final rule, effective January 1, 2027 for the PFS relative value file; weekly, every Thursday for the Medicare Coverage Database LCD export.

Key facts for G0105

Medicare payment
$378.10
PFS non-facility, national; facility $164.67
Coverage code
D
special coverage instructions apply
Practitioner MUE
1
MAI 2
OPPS status
SI T
Procedure or service, multiple reduction applies
NCCI PTP pairs
330
299 hospital outpatient
LCDs and articles
1 / 3

TL;DR

G0105 is a Level II code from the G section (procedures and professional services, temporary), in use since 1998: "Colorectal cancer screening; colonoscopy on individual at high risk". Medicare's October 2026 physician fee schedule pays G0105 $378.10 non-facility and $164.67 facility nationally, from 3.18 work, 7.73 practice-expense and 0.41 malpractice RVUs at the $33.4009 conversion factor. Qualifying APM participants get $379.98 at $33.5675. Global period 000 (0-day global period). MUE limits for G0105: practitioner 1 (MAI 2, Anatomic Consideration); hospital outpatient 1 (MAI 2, Anatomic Consideration). G0105 is a primary code for 1 add-on code (G0513). In the NCCI PTP files v323r0 G0105 appears in 20 practitioner pairs as column 2 and 310 as column 1 (most often with 0885T, 0886T, 45349), and in 20 hospital outpatient pairs as column 2 and 279 as column 1. 1 active LCD and 3 billing and coding articles list G0105 across 4 states: L34454 (Colonoscopy/Sigmoidoscopy/Proctosigmoidoscopy), A55069, A55227. HCPCS record: BETOS P8D (endoscopy - colonoscopy); pricing indicator 11; type of service 2 (surgery). 4 other active codes open with "Colorectal cancer screening"; related codes: G0104, G0121, G0327, G0328.

G0105 descriptor and code status

The October 2026 HCPCS Level II file describes G0105 as “Colorectal cancer screening; colonoscopy on individual at high risk”. It sits in the G section (procedures and professional services, temporary), listed with the other G codes. Although searches often call it the "G0105 CPT code", G0105 is a HCPCS Level II code maintained by CMS, not an AMA CPT code; both go in the same procedure-code field on the claim.

HCPCS file attributes of G0105
FieldValue
Short descriptorColorectal scrn; hi risk ind
Added to HCPCS1998-01-01
Last actionN (no maintenance), effective 1998-01-01
Coverage codeD: special coverage instructions apply
Pricing indicator11: physician fee schedule, priced with national RVUs
BETOS categoryP8D: endoscopy - colonoscopy
Type of service2: surgery

Medicare payment for G0105

Medicare's October 2026 physician fee schedule pays G0105 $378.10 non-facility and $164.67 facility nationally, from 3.18 work, 7.73 practice-expense and 0.41 malpractice RVUs at the $33.4009 conversion factor. Qualifying APM participants get $379.98 at $33.5675. Global period 000 (0-day global period). The amounts below are national figures from the October 2026 CMS files; the contractor applies the locality, rural or state adjustment and the beneficiary's cost sharing.

Physician fee schedule (RVU26D)

Status A: active: paid separately under the physician fee schedule when covered. Global period 000 (0-day global period); PC/TC indicator 0 (physician service; the professional/technical split does not apply).

PFS relative values and national payment for G0105
ComponentNon-facilityFacility
Work RVU3.183.18
Practice expense RVU7.731.34
Malpractice RVU0.410.41
Total RVUs11.324.93
National payment (CF $33.4009)$378.10$164.67
Qualifying APM participant (CF $33.5675)$379.98$165.49
  • Multiple procedures (modifier 51): standard multiple-procedure reduction (100%, then 50%)
  • Bilateral (modifier 50): 150% bilateral adjustment does not apply
  • Assistant at surgery: assistant at surgery may not be paid; co-surgeons: co-surgeons not permitted; team surgery: team surgeons not permitted
  • Physician supervision of diagnostic procedures: supervision concept does not apply

G0105 also carries 53 rows in the RVU file, priced separately from the global service.

Component rows for G0105
ModifierStatusNon-facilityFacility
53A$189.05$82.17

Hospital outpatient (OPPS Addendum B)

Status indicator T (Procedure or service, multiple reduction applies), APC 5311 (Level 1 Lower GI Procedures), national unadjusted payment $950.10 with a minimum unadjusted copayment of $0.00.

Ambulatory surgical center (Addendum AA)

Payment indicator A2 (Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight), national rate $510.49 at a payment weight of 9.0638. The multiple-procedure discount applies when it is billed with another ASC procedure.

Medically Unlikely Edits for G0105

MUE limits for G0105: practitioner 1 (MAI 2, Anatomic Consideration); hospital outpatient 1 (MAI 2, Anatomic Consideration). The practitioner MUE is a date-of-service policy edit: units above the limit deny even when split across lines, and appeals rarely succeed.

MUE values for G0105 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services12 Date of Service Edit: PolicyAnatomic Consideration
Facility outpatient hospital12 Date of Service Edit: PolicyAnatomic Consideration

The MUE lookup for G0105 shows every setting next to any other code on the same claim.

NCCI edits and add-on rules

In the practitioner PTP file v323r0, G0105 is the column-2 (bundled) code in 20 active pairs, 5% of which allow a modifier and the column-1 code in 310 (69% modifier-allowed); 304 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Mutually exclusive procedures.

Column-1 codes most often paired with G0105 (practitioner)
Column-1 codePairs
0885T (CPT; descriptor licensed by AMA)1
0886T (CPT; descriptor licensed by AMA)1
45349 (CPT; descriptor licensed by AMA)1
45378 (CPT; descriptor licensed by AMA)1
45379 (CPT; descriptor licensed by AMA)1
45380 (CPT; descriptor licensed by AMA)1
45381 (CPT; descriptor licensed by AMA)1
45382 (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into G0105 (practitioner)
Column-2 codePairs
0091U (CPT; descriptor licensed by AMA)1
0163U (CPT; descriptor licensed by AMA)1
0213T (CPT; descriptor licensed by AMA)1
0216T (CPT; descriptor licensed by AMA)1
0405U (CPT; descriptor licensed by AMA)1
0421U (CPT; descriptor licensed by AMA)1
0460U (CPT; descriptor licensed by AMA)1
0461U (CPT; descriptor licensed by AMA)1

In the hospital outpatient PTP file v323r0, G0105 is the column-2 (bundled) code in 20 active pairs, 5% of which allow a modifier and the column-1 code in 279 (89% modifier-allowed); 178 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Mutually exclusive procedures.

Column-1 codes most often paired with G0105 (hospital outpatient)
Column-1 codePairs
0885T (CPT; descriptor licensed by AMA)1
0886T (CPT; descriptor licensed by AMA)1
45349 (CPT; descriptor licensed by AMA)1
45378 (CPT; descriptor licensed by AMA)1
45379 (CPT; descriptor licensed by AMA)1
45380 (CPT; descriptor licensed by AMA)1
45381 (CPT; descriptor licensed by AMA)1
45382 (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into G0105 (hospital outpatient)
Column-2 codePairs
0091U (CPT; descriptor licensed by AMA)1
0163U (CPT; descriptor licensed by AMA)1
0213T (CPT; descriptor licensed by AMA)1
0216T (CPT; descriptor licensed by AMA)1
0405U (CPT; descriptor licensed by AMA)1
0421U (CPT; descriptor licensed by AMA)1
0460U (CPT; descriptor licensed by AMA)1
0461U (CPT; descriptor licensed by AMA)1

G0105 is a designated primary code for 1 add-on code (G0513).

Pair counts show exposure, not the answer for one claim. Check G0105 against a second code to see whether the pair bundles and whether a modifier can separate the services.

Medicare coverage policies for G0105

1 active Local Coverage Determination and 3 billing and coding articles list G0105. Each applies only in its contractor's jurisdiction, and the article carries the diagnosis codes that support the item or service.

Billing and Coding Articles listing G0105
ArticleTitleContractor(s)Related LCD
A55069Billing and Coding: Screening Colonoscopy Converted to a Diagnostic and/or Therapeutic ColonoscopyPalmetto GBAL34454
A55227Billing and Coding: Incomplete Colonoscopy/Failed ColonoscopyPalmetto GBAL34454
A56632Billing and Coding: Colonoscopy/Sigmoidoscopy/ProctosigmoidoscopyPalmetto GBAL34454

Denials to expect on G0105

the diagnosis or documentation does not meet the LCD or billing article that lists G0105

units of G0105 exceed the practitioner MUE of 1 per date of service

the modifier reported is inconsistent with the code

the claim lacks information needed to adjudicate the line, such as an order, NPI or required modifier

Where QuickIntell fits for G0105 claims

QuickCode supports qualified coder review of units, modifiers and NCCI pairs for G0105 before the claim leaves, and QuickRCM carries claim readiness and the denial follow-up when an edit or coverage policy is missed.

Frequently asked questions: HCPCS G0105

What does HCPCS code G0105 describe?

"Colorectal cancer screening; colonoscopy on individual at high risk" (short descriptor "Colorectal scrn; hi risk ind"), in the G section (procedures and professional services, temporary). Added 1998-01-01.

Is G0105 a CPT code?

No: CMS maintains G0105 in HCPCS Level II, while the AMA maintains CPT. People do search "G0105 CPT code", and it goes in the same procedure-code field.

What does Medicare pay for G0105?

Medicare's October 2026 physician fee schedule pays G0105 $378.10 non-facility and $164.67 facility nationally, from 3.18 work, 7.73 practice-expense and 0.41 malpractice RVUs at the $33.4009 conversion factor. Qualifying APM participants get $379.98 at $33.5675. Global period 000 (0-day global period).

Is G0105 an add-on code?

G0105 is a primary code for 1 add-on code (G0513).

How many units of G0105 can be billed per day?

MUE limits for G0105: practitioner 1 (MAI 2, Anatomic Consideration); hospital outpatient 1 (MAI 2, Anatomic Consideration). For the practitioner MUE (MAI 2), units above 1 deny for the whole day as a policy limit; denials arrive as CARC 151.

Does Medicare cover G0105?

Coverage code D (special coverage instructions apply). 1 active LCD and 3 billing and coding articles list G0105 across 4 states: L34454 (Colonoscopy/Sigmoidoscopy/Proctosigmoidoscopy), A55069, A55227.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

This page is an operational reference compiled from CMS publications: the HCPCS Level II file, the physician, DMEPOS and clinical laboratory fee schedules, OPPS and ASC addenda, NCCI MUE, PTP and add-on edit tables and the Medicare Coverage Database. Amounts are Medicare national figures before locality and state adjustment; Medicaid and commercial payers set their own. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.