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HCPCS C8921 · Level II · C code

C8921: Transthoracic echocardiography with contrast, HCPCS Level II C code

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: HCPCS Level II file: October 2026 (effective October 1, 2026); NCCI MUE tables: 2026 Q4 (effective October 1, 2026); NCCI PTP edits: v323r0 (2026 Q4) (effective October 1, 2026); OPPS Addendum B: October 2026 (effective October 1, 2026); Medicare Coverage Database LCD export: MCD release October 8, 2026 (effective October 4, 2026). Next CMS release: January 1, 2027 (quarterly update) for the HCPCS Level II file and NCCI MUE tables and NCCI PTP edits and OPPS Addendum B; weekly, every Thursday for the Medicare Coverage Database LCD export.

Key facts for C8921

Medicare payment
$800.90
OPPS rate, SI S
Coverage code
D
special coverage instructions apply
Facility outpatient MUE
1
MAI 3
OPPS status
SI S
Procedure or service, not discounted when multiple
NCCI PTP pairs
296
293 hospital outpatient
LCDs and articles
2 / 2

TL;DR

HCPCS Level II C8921 reads "Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; complete" in the October 2026 file; it dates from 2008. Hospital outpatient departments are paid $800.90 for C8921 under status indicator S, APC 5573 (Level 3 Imaging with Contrast), minimum unadjusted copayment $160.18 (October 2026 Addendum B). Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Service/Procedure); hospital outpatient 1 (MAI 3, Nature of Service/Procedure). C8921 is a primary code for 4 add-on codes (93320, 93321, 93325, 93356). In the NCCI PTP files v323r0 C8921 appears in 274 practitioner pairs as column 2 and 22 as column 1 (most often with 00100, 00102, 00103), and in 274 hospital outpatient pairs as column 2 and 19 as column 1. 2 active LCDs and 2 billing and coding articles list C8921 across 7 states: L33577 (Transthoracic Echocardiography (TTE)), L34338 (Transthoracic Echocardiography (TTE)), A56781, A57306. HCPCS record: BETOS I3C (ultrasound - heart); pricing indicator 53; type of service 4 (diagnostic radiology). 5 other active codes open with "Transthoracic echocardiography with contrast"; related codes: C8924, C8928, C8929, C8922.

C8921 descriptor and code status

The October 2026 HCPCS Level II file describes C8921 as “Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; complete”. It sits in the C section (hospital outpatient prospective payment system, temporary codes), listed with the other C codes.

HCPCS file attributes of C8921
FieldValue
Short descriptorTte w or w/o fol w/cont, com
Added to HCPCS2008-01-01
Last actionN (no maintenance), effective 2008-01-01
Coverage codeD: special coverage instructions apply
Pricing indicator53: statute
BETOS categoryI3C: ultrasound - heart
Type of service4: diagnostic radiology
Statute1833(t)(2)

Medicare payment for C8921

Hospital outpatient departments are paid $800.90 for C8921 under status indicator S, APC 5573 (Level 3 Imaging with Contrast), minimum unadjusted copayment $160.18 (October 2026 Addendum B). The amounts below are national figures from the October 2026 CMS files; the contractor applies the locality, rural or state adjustment and the beneficiary's cost sharing.

Hospital outpatient (OPPS Addendum B)

Status indicator S (Procedure or service, not discounted when multiple), APC 5573 (Level 3 Imaging with Contrast), national unadjusted payment $800.90 with a minimum unadjusted copayment of $160.18.

Medically Unlikely Edits for C8921

Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Service/Procedure); hospital outpatient 1 (MAI 3, Nature of Service/Procedure). The facility outpatient MUE is a date-of-service clinical edit: units above the limit deny but can be paid on appeal with documentation.

MUE values for C8921 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services13 Date of Service Edit: ClinicalNature of Service/Procedure
Facility outpatient hospital13 Date of Service Edit: ClinicalNature of Service/Procedure

The MUE lookup for C8921 shows every setting next to any other code on the same claim.

NCCI edits and add-on rules

In the practitioner PTP file v323r0, C8921 is the column-2 (bundled) code in 274 active pairs, 99% of which allow a modifier and the column-1 code in 22 (82% modifier-allowed); 17 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Standard preparation/monitoring services for anesthesia.

Column-1 codes most often paired with C8921 (practitioner)
Column-1 codePairs
00100 (CPT; descriptor licensed by AMA)1
00102 (CPT; descriptor licensed by AMA)1
00103 (CPT; descriptor licensed by AMA)1
00104 (CPT; descriptor licensed by AMA)1
00120 (CPT; descriptor licensed by AMA)1
00124 (CPT; descriptor licensed by AMA)1
00126 (CPT; descriptor licensed by AMA)1
00140 (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into C8921 (practitioner)
Column-2 codePairs
0708T (CPT; descriptor licensed by AMA)1
0709T (CPT; descriptor licensed by AMA)1
36000 (CPT; descriptor licensed by AMA)1
36005 (CPT; descriptor licensed by AMA)1
36410 (CPT; descriptor licensed by AMA)1
36591 (CPT; descriptor licensed by AMA)1
36592 (CPT; descriptor licensed by AMA)1
76998 (CPT; descriptor licensed by AMA)1

In the hospital outpatient PTP file v323r0, C8921 is the column-2 (bundled) code in 274 active pairs, 99% of which allow a modifier and the column-1 code in 19 (95% modifier-allowed); 17 earlier pairs have been deleted. CMS's most frequent rationale for the bundled pairs: Standard preparation/monitoring services for anesthesia.

Column-1 codes most often paired with C8921 (hospital outpatient)
Column-1 codePairs
00100 (CPT; descriptor licensed by AMA)1
00102 (CPT; descriptor licensed by AMA)1
00103 (CPT; descriptor licensed by AMA)1
00104 (CPT; descriptor licensed by AMA)1
00120 (CPT; descriptor licensed by AMA)1
00124 (CPT; descriptor licensed by AMA)1
00126 (CPT; descriptor licensed by AMA)1
00140 (CPT; descriptor licensed by AMA)1
Column-2 codes bundled into C8921 (hospital outpatient)
Column-2 codePairs
0708T (CPT; descriptor licensed by AMA)1
0709T (CPT; descriptor licensed by AMA)1
36000 (CPT; descriptor licensed by AMA)1
36005 (CPT; descriptor licensed by AMA)1
36410 (CPT; descriptor licensed by AMA)1
76998 (CPT; descriptor licensed by AMA)1
93040 (CPT; descriptor licensed by AMA)1
93041 (CPT; descriptor licensed by AMA)1

C8921 is a designated primary code for 4 add-on codes (93320, 93321, 93325, 93356).

Pair counts show exposure, not the answer for one claim. Check C8921 against a second code to see whether the pair bundles and whether a modifier can separate the services.

Medicare coverage policies for C8921

2 active Local Coverage Determinations and 2 billing and coding articles list C8921. Each applies only in its contractor's jurisdiction, and the article carries the diagnosis codes that support the item or service.

Billing and Coding Articles listing C8921
ArticleTitleContractor(s)Related LCD
A56781Billing and Coding: Transthoracic Echocardiography (TTE)Wellpoint FederalL33577
A57306Billing and Coding: Transthoracic Echocardiography (TTE)CGS Administrators, LLCL34338

Denials to expect on C8921

the diagnosis or documentation does not meet the LCD or billing article that lists C8921

units of C8921 exceed the facility outpatient MUE of 1 per date of service

the modifier reported is inconsistent with the code

the claim lacks information needed to adjudicate the line, such as an order, NPI or required modifier

Where QuickIntell fits for C8921 claims

QuickCode supports qualified coder review of units, modifiers and NCCI pairs for C8921 before the claim leaves, and QuickRCM carries claim readiness and the denial follow-up when an edit or coverage policy is missed.

Frequently asked questions: HCPCS C8921

What does HCPCS code C8921 describe?

"Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; complete" (short descriptor "Tte w or w/o fol w/cont, com"), in the C section (hospital outpatient prospective payment system, temporary codes). Added 2008-01-01.

Is C8921 a CPT code?

No. C8921 is a CMS HCPCS Level II code; CPT codes are the AMA's five-character set.

What does Medicare pay for C8921?

Hospital outpatient departments are paid $800.90 for C8921 under status indicator S, APC 5573 (Level 3 Imaging with Contrast), minimum unadjusted copayment $160.18 (October 2026 Addendum B).

Is C8921 an add-on code?

C8921 is a primary code for 4 add-on codes (93320, 93321, 93325, 93356).

How many units of C8921 can be billed per day?

Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Service/Procedure); hospital outpatient 1 (MAI 3, Nature of Service/Procedure). For the facility outpatient MUE (MAI 3), units above 1 deny for the day but can be paid on appeal with documentation; denials arrive as CARC 151.

Does Medicare cover C8921?

Coverage code D (special coverage instructions apply). 2 active LCDs and 2 billing and coding articles list C8921 across 7 states: L33577 (Transthoracic Echocardiography (TTE)), L34338 (Transthoracic Echocardiography (TTE)), A56781, A57306.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

This page is an operational reference compiled from CMS publications: the HCPCS Level II file, the physician, DMEPOS and clinical laboratory fee schedules, OPPS and ASC addenda, NCCI MUE, PTP and add-on edit tables and the Medicare Coverage Database. Amounts are Medicare national figures before locality and state adjustment; Medicaid and commercial payers set their own. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.