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HCPCS C2621 · Level II · C code

C2621: Pacemaker, other than single or dual chamber (implantable), HCPCS Level II C code

Compiled from CMS files by the QuickIntell RCM Editorial Team · Data effective · Method: reference methodology · Report a data correction

Data currency: HCPCS Level II file: October 2026 (effective October 1, 2026); NCCI MUE tables: 2026 Q4 (effective October 1, 2026); NCCI PTP edits: v323r0 (2026 Q4) (effective October 1, 2026); OPPS Addendum B: October 2026 (effective October 1, 2026). Next CMS release: January 1, 2027 (quarterly update).

Key facts for C2621

Medicare payment
none in these files
no PFS, DMEPOS, CLFS, OPPS or ASC amount; pricing indicator 53
Coverage code
D
special coverage instructions apply
Practitioner MUE
1
MAI 3
OPPS status
SI N
Items and Services packaged into APC rates
NCCI PTP pairs
0
practitioner file
LCDs and articles
0 / 0

TL;DR

C2621 is a Level II code from the C section (hospital outpatient prospective payment system, temporary codes), in use since 2001: "Pacemaker, other than single or dual chamber (implantable)". None of the October 2026 PFS, DMEPOS, CLFS, OPPS or ASC files lists a national amount for C2621; its HCPCS pricing indicator is 53 (statute). Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Equipment); hospital outpatient 1 (MAI 3, Nature of Equipment). No current LCD or billing article lists C2621; its HCPCS coverage code is D (special coverage instructions apply). OPPS status indicator N: Items and Services packaged into APC rates. HCPCS record: BETOS D1A (medical/surgical supplies); pricing indicator 53; type of service 9 (other medical items or services), S (surgical dressings or other medical supplies). 5 other active codes open with "Pacemaker"; related codes: C1786, C1785, C1605, C2620.

C2621 descriptor and code status

The October 2026 HCPCS Level II file describes C2621 as “Pacemaker, other than single or dual chamber (implantable)”. It sits in the C section (hospital outpatient prospective payment system, temporary codes), listed with the other C codes.

HCPCS file attributes of C2621
FieldValue
Short descriptorPmkr, other than sing/dual
Added to HCPCS2001-04-01
Last actionN (no maintenance), effective 2004-01-01
Coverage codeD: special coverage instructions apply
Pricing indicator53: statute
BETOS categoryD1A: medical/surgical supplies
Type of service9: other medical items or services; S: surgical dressings or other medical supplies
Statute1833(T)

Medicare payment for C2621

None of the October 2026 PFS, DMEPOS, CLFS, OPPS or ASC files lists a national amount for C2621; its HCPCS pricing indicator is 53 (statute). The amounts below are national figures from the October 2026 CMS files; the contractor applies the locality, rural or state adjustment and the beneficiary's cost sharing.

Hospital outpatient (OPPS Addendum B)

Status indicator N (Items and Services packaged into APC rates), with no separate OPPS payment rate.

Ambulatory surgical center (Addendum BB)

Payment indicator N1 (Packaged service/item; no separate payment made).

Medically Unlikely Edits for C2621

Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Equipment); hospital outpatient 1 (MAI 3, Nature of Equipment). The practitioner MUE is a date-of-service clinical edit: units above the limit deny but can be paid on appeal with documentation.

MUE values for C2621 by setting
SettingMUE (units/DOS)MAICMS rationale
Practitioner services13 Date of Service Edit: ClinicalNature of Equipment
Facility outpatient hospital13 Date of Service Edit: ClinicalNature of Equipment

The MUE lookup for C2621 shows every setting next to any other code on the same claim.

NCCI edits and add-on rules

No active practitioner PTP pair lists C2621 in v323r0.

C2621 is neither an add-on code nor a designated primary code in the 2026 Q4 NCCI add-on edit file.

Pair counts show exposure, not the answer for one claim. Check C2621 against a second code to see whether the pair bundles and whether a modifier can separate the services.

Medicare coverage policies for C2621

No current LCD or billing and coding article lists C2621. The HCPCS coverage code D means special coverage instructions apply, and any National Coverage Determination for the service still applies.

Denials to expect on C2621

the service is not reasonable and necessary for the diagnosis on the claim

units of C2621 exceed the practitioner MUE of 1 per date of service

the modifier reported is inconsistent with the code

the claim lacks information needed to adjudicate the line, such as an order, NPI or required modifier

Where QuickIntell fits for C2621 claims

QuickCode supports qualified coder review of units, modifiers and NCCI pairs for C2621 before the claim leaves, and QuickRCM carries claim readiness and the denial follow-up when an edit or coverage policy is missed.

Frequently asked questions: HCPCS C2621

What does HCPCS code C2621 describe?

"Pacemaker, other than single or dual chamber (implantable)" (short descriptor "Pmkr, other than sing/dual"), in the C section (hospital outpatient prospective payment system, temporary codes). Added 2001-04-01; last action N (no maintenance) effective 2004-01-01.

Is C2621 a CPT code?

No. C2621 is a CMS HCPCS Level II code; CPT codes are the AMA's five-character set.

What does Medicare pay for C2621?

None of the October 2026 PFS, DMEPOS, CLFS, OPPS or ASC files lists a national amount for C2621; its HCPCS pricing indicator is 53 (statute).

How many units of C2621 can be billed per day?

Its 2026 Q4 MUEs per date of service: practitioner 1 (MAI 3, Nature of Equipment); hospital outpatient 1 (MAI 3, Nature of Equipment). For the practitioner MUE (MAI 3), units above 1 deny for the day but can be paid on appeal with documentation; denials arrive as CARC 151.

Does Medicare cover C2621?

No current LCD or billing article lists C2621; its HCPCS coverage code is D (special coverage instructions apply).

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-10. Verify against the primary file before billing or contracting decisions. The reference methodology explains how each figure is computed from these files.

Disclaimer

This page is an operational reference compiled from CMS publications: the HCPCS Level II file, the physician, DMEPOS and clinical laboratory fee schedules, OPPS and ASC addenda, NCCI MUE, PTP and add-on edit tables and the Medicare Coverage Database. Amounts are Medicare national figures before locality and state adjustment; Medicaid and commercial payers set their own. CPT codes are shown as numbers only; CPT descriptors are copyright AMA. Nothing here is legal, clinical or billing advice.

Found a figure that does not match the CMS file? Report a data correction with the CMS file and the value you expected; the request reaches the editorial team through the contact form.