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LCD L33445: Removal of Benign and Malignant Skin Lesions

LCD L33445, Removal of Benign and Malignant Skin Lesions, is the Local Coverage Determination that Palmetto GBA applies to claims from 7 states (AL, GA, NC, SC, TN, VA, WV), effective 2025-10-23 and first in force 2015-10-01. The policy text runs 514 words, and its billing and coding article A56346 lists 251 ICD-10-CM codes that support medical necessity for 68 procedure codes. No other contractor publishes a policy with this title.

QuickIntell editorial content · Legacy registry date · Review not verified

Data effective
Data currency: Medicare Coverage Database LCD export release of September 24, 2026 (effective September 20, 2026). Next CMS release: weekly (Thursdays) for the MCD.
Contractor
Palmetto GBA
States and territories
7
AL GA NC SC TN VA WV
Revision effective
2025-10-23
Original effective
2015-10-01
Policy text
514 words
Covered ICD-10 codes (articles)
251

Where this LCD applies

Each contract number is a jurisdiction on the remittance; the policy binds claims processed under these contracts and no others.

Contracts that apply LCD L33445
ContractContractorTypeStates
11201Palmetto GBAA and B and HHH MACSC
11301Palmetto GBAA and B and HHH MACVA
11401Palmetto GBAA and B and HHH MACWV
11501Palmetto GBAA and B and HHH MACNC
11202Palmetto GBAA and B and HHH MACSC
11302Palmetto GBAA and B and HHH MACVA
11402Palmetto GBAA and B and HHH MACWV
11502Palmetto GBAA and B and HHH MACNC
10111Palmetto GBAA and B MACAL
10211Palmetto GBAA and B MACGA
10311Palmetto GBAA and B MACTN
10112Palmetto GBAA and B MACAL
10212Palmetto GBAA and B MACGA
10312Palmetto GBAA and B MACTN

Billing and coding: diagnoses and procedure codes

Since 2019 the codes live in the companion article rather than the LCD. Billing and Coding A56346 (Billing and Coding: Removal of Benign and Malignant Skin Lesions) carries the diagnosis and procedure lists the contractor loads as the claims edit. CPT codes are shown as bare numbers because the descriptors are licensed by the AMA; HCPCS Level II descriptors are public and shown.

A56346: Billing and Coding: Removal of Benign and Malignant Skin Lesions (Billing and Coding, effective 2026-07-01)

Covered ICD-10-CM codes
251
1 group
Non-covered ICD-10-CM codes
0
Procedure codes listed
68
Full article
cms.gov record
First 24 covered ICD-10-CM codes in A56346
ICD-10-CMDescription (FY2027)
A63.0—
B07.0—
B07.8—
B07.9—
B08.1—
C43.0—
C43.111—
C43.112—
C43.121—
C43.122—
C43.21—
C43.22—
C43.30—
C43.31—
C43.39—
C43.4—
C43.51—
C43.52—
C43.59—
C43.61—
C43.62—
C43.71—
C43.72—
C43.8—

Procedure codes: 11300, 11301, 11302, 11303, 11305, 11306, 11307, 11308, 11310, 11311, 11312, 11313, 11400, 11401, 11402, 11403, 11404, 11406, 11420, 11421, 11422, 11423, 11424, 11426, 11440, 11441, 11442, 11443, 11444, 11446, 11600, 11601, 11602, 11603, 11604, 11606, 11620, 11621, 11622, 11623 and 28 more in the article.

Coverage indications, limitations and medical necessity

Benign skin lesions are common in the elderly and are sometimes removed at the patient's request. Removal of certain benign skin lesions that do not pose a threat to health or function are considered cosmetic, and as such, are not covered by the Medicare program (statutory exclusion). This local coverage determination (LCD) describes the medical conditions for which skin lesion removal using one of the services (e.g., shaving, removal, destruction, etc.) listed in the CPT ® section of the related billing and coding article A56346 would be medically necessary and would therefore not be excluded.

Medicare would consider the removal of any malignant lesion to be medically necessary. Actinic keratosis removals are covered as per the requirements indicated in the CMS Internet-Only Manual, Pub. 100-03, Medicare National Coverage Determinations (NCD) Manual, Chapter 1, Part 4, §250.4.

There may be instances in which the removal of benign seborrheic keratoses, sebaceous cysts and viral warts is medically appropriate. Medicare will, therefore, consider their removal as medically necessary and not cosmetic if one or more of the following conditions are present and clearly documented in the medical record:

• The lesion has one or more of the following characteristics:

• Bleeding

• Persistent or intense itching

• Pain

• The lesion has physical evidence of inflammation (purulence, oozing, edema, erythema, etc.)

• The lesion obstructs an orifice or clinically restricts vision

• There is clinical uncertainty as to the likely diagnosis, particularly where malignancy is a realistic consideration based on lesional appearance, such as increased rate of growth and/or color changes

• The lesion is in an anatomical region subject to recurrent physical trauma and there is documentation that such trauma has in fact occurred

• Wart destruction will be covered if it falls under one of the conditions of the first five bullets above. In addition, because warts are a viral infection of the skin, wart destruction will be covered when any one of the following clinical circumstances is present:

• Periocular warts associated with chronic recurrent conjunctivitis thought secondary to lesional virus shedding

• Warts of recent origin in immunosuppressed patients

Lesions in sensitive anatomic locations that are non-problematic do not qualify for removal coverage on the basis of location alone.

The type of removal is at the discretion of the treating physician and the appropriateness of the technique used will not be a factor in deciding if a lesion merits removal. However, a benign lesional excision must have medical record documentation as to why an excisional removal, other than for cosmetic purposes, was the surgical procedure of choice.

The decision to submit a specimen for pathologic interpretation will be independent of the decision to remove or not remove the lesion. It is assumed, however, that a tissue diagnosis will be part of the medical record when an ultimately benign lesion is removed based on physician uncertainty as to the final clinical diagnosis.

Office visits will be covered when the diagnosis of a benign skin lesion(s) is made, even if the removal of a particular lesion(s) is not medically indicated and is therefore not done.

Summary of evidence (opening)

N/A

the full summary and analysis of evidence are in the CMS record.

Dates, lineage and related policies

Original determination effective
2015-10-01
Current revision effective
2025-10-23
Last reviewed by the contractor
2025-09-15
MCD version
79
Derived from
L31754

The contractor lists one National Coverage Determination as related: NCD 250.4 Treatment of Actinic Keratosis. Where an NCD speaks, it controls; the LCD can only address what the NCD leaves open.

Using this policy on a claim

Match the documented indication to the covered indications above before the service is scheduled, carry a diagnosis from the article's covered list on the claim line, and keep the elements the documentation section asks for in the record, because the contractor can request it later through medical review. A denial under this policy arrives as CARC 50 with remark N115; the LCD lookup guide walks through the appeal path and the Advance Beneficiary Notice rules, and the Palmetto GBA hub lists every other active policy from the same contractor.

Frequently asked questions

What does LCD L33445 cover?

Benign skin lesions are common in the elderly and are sometimes removed at the patient's request. Removal of certain benign skin lesions that do not pose a threat to health or function are considered cosmetic, and as such, are not covered by the Medicare program (statutory exclusion). This local coverage determination (LCD) describes the medical conditions for which skin lesion removal using one of the services… The full indications and limitations are reproduced on this page from the CMS Medicare Coverage Database export of September 24, 2026.

Which states does LCD L33445 apply to?

Palmetto GBA applies it to Medicare claims in AL, GA, NC, SC, TN, VA, WV. A Local Coverage Determination binds only the contractor that wrote it; the same service in another jurisdiction is judged under that contractor's own policy or, where none exists, claim by claim.

Which diagnosis codes support medical necessity under LCD L33445?

The companion billing and coding article A56346 lists 251 ICD-10-CM codes in 1 group that support medical necessity; the first 24 appear on this page and the complete list is in the article on cms.gov.

How do I appeal a denial under LCD L33445?

The remittance carries claim adjustment reason code 50 with remark code N115, naming the LCD. Compare the documented indication with the policy's covered indications and the article's diagnosis list, then file a redetermination within 120 days with the record attached; if the service genuinely falls outside the policy, the patient can be billed only when a valid Advance Beneficiary Notice was obtained before the service.

Sources

Every figure on this page is taken from the CMS publications below, as released by the Centers for Medicare & Medicaid Services. Projection built 2026-10-02. Verify against the primary file before billing or contracting decisions.

Disclaimer

The policy text and code lists are reproduced from the CMS Medicare Coverage Database export as an operational reference. Verify against the current LCD and article on cms.gov before billing; coverage depends on the full record and the contractor. Not legal, clinical or billing advice.